Dengue epidemic in the State of Rio Grande do Norte, Brazil, in 1997

被引：27
|
作者：
Cunha, RV
Schatzmayr, HG
Miagostovich, MP
Barbosa, AMA
Paiva, FG
Miranda, RMO
Ramos, CCF
Coelho, JCO
dos Santos, FB
Nogueira, RMR
机构：
[1] Univ Fed Mato Grosso Sul, Disciplina Doencas Infecciosas & Parasitarias, Campo Grande, MS, Brazil
[2] Inst Oswaldo Cruz FIOCRUZ, Rio De Janeiro, Brazil
[3] Inst Oswaldo Cruz FIOCRUZ, Dept Virol, Lab Flavivirus, Rio De Janeiro, Brazil
[4] IOC FIOCRUZ, Hosp Evandro Chagas, Manguinho, Brazil
来源：
TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE | 1999年 / 93卷 / 03期
关键词：
dengue; DEN-1; DEN-2; dengue haemorrhagic fever; risk factors; Brazil;
D O I：
10.1016/S0035-9203(99)90008-1
中图分类号：
R1 [预防医学、卫生学];
学科分类号：
1004 ; 120402 ;
摘要：
During 1997 a large dengue epidemic occurred in Rio Grande do Norte, a State in north-east Brazil. The cocirculation of dengue virus type 1 and dengue virus type 2 was demonstrated by virus isolation in Aedes albopictus clone C6/36 cell-line and by reverse transcriptase-polymerase chain reaction (RT-PCR). IgM capture enzyme-linked immunosorbent assay confirmed 52.3% of the 8105 studied cases and dengue antigen was demonstrated by immunohistochemical reaction on hepatocytes from 2 out of 5 fatal cases studied. Individual risk factors for development of dengue haemorrhagic fever/dengue shock syndrome, such as hypertension, diabetes mellitus and bronchial asthma, are discussed.
引用
收藏
页码：247 / 249
页数：3
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