A simple and efficient approach for the palladium-catalyzed ligand-free Suzuki reaction in water

被引：100
|
作者：
Liu, Chun [1 ]
Zhang, Yixia [1 ]
Liu, Ning [1 ]
Qiu, Jieshan [1 ]
机构：
[1] Dalian Univ Technol, State Key Lab Fine Chem, Dalian 116024, Peoples R China
来源：
GREEN CHEMISTRY | 2012年 / 14卷 / 11期
基金：
中国国家自然科学基金;
关键词：
CROSS-COUPLING REACTIONS; LINKED AMPHIPHILIC POLYMER; ARYL CHLORIDES; ARYLBORONIC ACIDS; MIYAURA REACTION; AQUEOUS-MEDIA; GREEN CHEMISTRY; PURE WATER; ASSEMBLED COMPLEX; NANOPARTICLES;
D O I：
10.1039/c2gc36098e
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A general and efficient protocol is described for the palladium-catalyzed ligand-free and aerobic Suzuki reaction in water in the absence of any additive. The results demonstrate that the base played a crucial role in the high efficiency. The Pd(OAc)(2)/(i-Pr)(2)NH/H2O system showed the highest catalytic activity towards the Suzuki reaction of a wide range of aryl halides bearing hydrophilic or hydrophobic groups.
引用
收藏
页码：2999 / 3003
页数：5
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