Sister chromatids caught in the cohesin trap

被引：2
|
作者：
Cipak, Lubos [1 ]
Spirek, Mario [1 ]
Gregan, Juraj [1 ]
机构：
[1] Univ Vienna, Dept Chromosome Biol, Max F Perutz Labs, A-1030 Vienna, Austria
来源：
NATURE STRUCTURAL & MOLECULAR BIOLOGY | 2008年 / 15卷 / 09期
基金：
奥地利科学基金会;
关键词：
D O I：
10.1038/nsmb0908-899
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Cohesin is a large ring-shaped protein complex that mediates cohesion between sister chromatids. New experiments show that the sister chromatids of a minichromosome are entrapped by monomeric cohesin rings, thus excluding the possibility that sister chromatid cohesion is mediated by nontopological interactions between cohesin complexes.
引用
收藏
页码：899 / 900
页数：2
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