Immunology Insights Into Cardiac Allograft Rejection

被引：3
|
作者：
Savasta, Marcello [1 ]
Lentini, Salvatore [1 ]
机构：
[1] Univ Messina, Policlin G Martino Univ Hosp, Cardiovasc & Thorac Dept, I-98100 Messina, Italy
来源：
REVIEWS IN CARDIOVASCULAR MEDICINE | 2011年 / 12卷 / 02期
关键词：
Immunology; Heart transplantation; Surgery; Complications; Rejection; Coronary artery pathology; Pharmacology; Physiology; HEART-TRANSPLANT RECIPIENTS; ALEMTUZUMAB CAMPATH-1H; INTERNATIONAL-SOCIETY; LUNG-TRANSPLANTATION; CYCLOSPORINE-A; TACROLIMUS; TOLERANCE; RETRANSPLANTATION; VASCULOPATHY; MULTICENTER;
D O I：
10.3909/ricm0562
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Despite long-term complications from chronic immunosuppressive therapy, the phenomenon of chronic rejection is still a limitation in cardiac allograft recipients. In this review, starting from basic immunologic concepts, we analyze the mechanisms involved in rejection following heart transplantation, with particular emphasis on chronic rejection manifested as cardiac allograft vasculopathy (CAV). Etiopathogenesis of CAV and diagnostic imaging studies are also discussed. (C) 2011 MedReviews (R), LLC
引用
收藏
页码：E68 / E76
页数：9
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