Pd-Catalyzed β-Selective Direct C-H Bond Arylation of Thiophenes with Aryltrimethylsilanes

被引：87
|
作者：
Funaki, Kenji [1 ]
Sato, Tetsuo [1 ,2 ]
Oi, Shuichi [1 ,2 ]
机构：
[1] Tohoku Univ, Grad Sch Engn, Dept Appl Chem, Aoba Ku, Sendai, Miyagi 9808579, Japan
[2] Tohoku Univ, Environm Conservat Res Inst, Aoba Ku, Sendai, Miyagi 9808579, Japan
来源：
ORGANIC LETTERS | 2012年 / 14卷 / 24期
关键词：
CROSS-COUPLING REACTIONS; ARYL HALIDES; DERIVATIVES; SILICON;
D O I：
10.1021/ol3029109
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Direct arylation of thiophenes and benzothiophenes with aryltrimethylsilanes was effectively catalyzed by PdCl2(MeCN)(2) in the presence of CuCl2 as an oxidant. The reaction preferentially occurred at the beta-position of both thiophenes and benzothiophenes.
引用
收藏
页码：6186 / 6189
页数：4
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