Protective effects of royal jelly on testicular torsion induced ischaemia reperfusion injury in rats

被引：10
|
作者：
Abbaszadeh, Abolfazl [1 ]
Assadollahi, Vahideh [2 ]
Alasvand, Masoud [2 ]
Anbari, Khatereh [3 ]
Tavakoli, Negin [4 ]
Gholami, Mohammadreza [5 ]
机构：
[1] Lorestan Univ Med Sci, Razi Herbal Med Res Ctr, Dept Surg, Khorramabad, Iran
[2] Kurdistan Univ Med Sci, Canc & Immunol Res Ctr, Res Inst Hlth Dev, Sanandaj, Iran
[3] Lorestan Univ Med Sci, Dept Social Med, Khorramabad, Iran
[4] Lorestan Univ Med Sci, Student Res Comm, Khorramabad, Iran
[5] Kermanshah Univ Med Sci, Med Biol Res Ctr, Kermanshah 6714869914, Iran
来源：
ANDROLOGIA | 2020年 / 52卷 / 09期
关键词：
ischaemia-reperfusion; royal jelly; testis; torsion; HISTOPATHOLOGICAL CHANGES; REPRODUCTIVE-PERFORMANCE; FUNCTIONAL-PROPERTIES; OXIDATIVE STRESS; SEMINAL PLASMA; ANTIOXIDANT; MECHANISMS; PARAMETERS; QUERCETIN; DETORSION;
D O I：
10.1111/and.13716
中图分类号：
R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
摘要：
This study was performed to investigate the protective effects of royal jelly (RJ) on a testicular torsion-induced ischaemia/reperfusion (I/R) injury in adult rats. A total of 40 male Wistar rats were divided into four groups, including 10 rats in each group: Group 1 (sham), Group 2 (Control), group 3 (I/R rats treated with 100 mg/kg RJ for 50 days after torsion) and group 4( I/R rats treated with 20 mg/kg vitamin C for 50 days after torsion). Testicular torsion was created by rotating the right testes 720 degrees a clockwise direction for 90 min. The levels of testosterone were measured by ELISA. Pathological evaluation, mean maturity and quality of the seminiferous tubules were used. Results showed that the testicular histopathology standards and testosterone levels changes were statistically significant in groups 3 and 4. The results obtained in this study may suggest that RJ like vitamin C had protective effects on a testicular ischaemia/reperfusion-induced injury in rats.
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页数：7
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