Atmospheric pressure matrix-assisted laser desorption/ionisation mass spectrometry: A review

被引：22
|
作者：
Creaser, CS [1 ]
Ratcliffe, L [1 ]
机构：
[1] Nottingham Trent Univ, Sch Biomed & Nat Sci, Interdisciplinary Biomed Res Ctr, Nottingham NG11 8NS, England
来源：
CURRENT ANALYTICAL CHEMISTRY | 2006年 / 2卷 / 01期
关键词：
atmospheric pressure; MALDI; mass spectrometry;
D O I：
10.2174/157341106775197420
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
Atmospheric pressure matrix-assisted laser desorption/ionization (AP-MALDI) was first introduced in 1999. In the last few years, there has been a rapid growth in publications describing the development and application of AP MALDI to the mass spectrometric analysis of peptides, polymers and oligosaccharides. This short review discusses recent advances in AP-MALDI, focusing on the analysis of biomolecules and the relative performance of MALDI at atmospheric pressure and in vacuo.
引用
收藏
页码：9 / 15
页数：7
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