Immunotherapy for the Management of Advanced Melanoma: The Next Steps

被引：12
|
作者：
Zikich, Dragoslav [1 ]
Schachter, Jacob [1 ]
Besser, Michal J. [1 ,2 ]
机构：
[1] Chaim Sheba Med Ctr, Ella Inst Melanoma, IL-52621 Ramat Gan, Israel
[2] Tel Aviv Univ, Sackler Sch Med, Dept Clin Microbiol & Immunol, IL-69978 Tel Aviv, Israel
来源：
AMERICAN JOURNAL OF CLINICAL DERMATOLOGY | 2013年 / 14卷 / 04期
关键词：
TUMOR-INFILTRATING LYMPHOCYTES; ADOPTIVE CELL TRANSFER; METASTATIC MELANOMA; T-CELLS; INTERLEUKIN-2; THERAPY; MALIGNANT-MELANOMA; ANTITUMOR IMMUNITY; CANCER REGRESSION; REGULATORY T; NK CELLS;
D O I：
10.1007/s40257-013-0013-0
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
Melanoma is an immunogenic tumor that can induce a natural immune response. A number of immunotherapy-based approaches have been developed over the past decades, and certain degrees of effectiveness were achieved by the use of cytokines, adoptive cell transfer and T-cell immune modulators. Currently, interleukin-2 and the immune stimulatory antibody, ipilimumab, are the only two approved immunotherapies for metastatic melanoma, but various new therapies are in promising developmental stages. This comprehensive review will discuss the latest achievements of immunotherapy and emerging directions for the management of advanced melanoma.
引用
收藏
页码：261 / 272
页数：12
相关论文
共 50 条
  • [21] Genomic analyses and immunotherapy in advanced melanoma
    Hodi, F. Stephen
    Wolchok, Jedd D.
    Schadendorf, Dirk
    Larkin, James
    Qian, Max
    Saci, Abdel
    Young, Tina C.
    Srinivasan, Sujaya
    Chang, Han
    Wind-Rotolo, Megan
    Rizzo, Jasmine I.
    Jackson, Donald G.
    Ascierto, Paolo A.
    [J]. CANCER RESEARCH, 2019, 79 (13)
  • [22] Hyperprogression in advanced melanoma is not restricted to immunotherapy
    Yang, Fan
    Xu, Nan
    [J]. EUROPEAN JOURNAL OF CANCER, 2024, 199
  • [23] Immunotherapy for advanced melanoma: Fulfilling the promise
    Gogas, Helen
    Polyzos, Aristidis
    Kirkwood, John
    [J]. CANCER TREATMENT REVIEWS, 2013, 39 (08) : 879 - 885
  • [24] Revolutionizing treatment of advanced melanoma with immunotherapy
    Carreau, Nicole
    Pavlick, Anna
    [J]. SURGICAL ONCOLOGY-OXFORD, 2022, 42
  • [25] A New Combination Immunotherapy in Advanced Melanoma
    Frampton, Adam E.
    Sivakumar, Shivan
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2022, 386 (01): : 91 - 92
  • [26] Immunotherapy for advanced melanoma: future directions
    Valpione, Sara
    Campana, Luca G.
    [J]. IMMUNOTHERAPY, 2016, 8 (02) : 199 - 209
  • [27] Hyperprogression in advanced melanoma is not restricted to immunotherapy
    Fournier, Marie
    Mortier, Laurent
    Dereure, Olivier
    Dalac, Sophie
    Oriano, Bastien
    Dalle, Stephane
    Lebbe, Celeste
    [J]. EUROPEAN JOURNAL OF CANCER, 2023, 193
  • [28] Immunotherapy in advanced cutaneous melanoma patients
    Mackiewicz, Jacek
    Krokowicz, Lukasz
    [J]. MENOPAUSE REVIEW-PRZEGLAD MENOPAUZALNY, 2013, 12 (05): : 429 - 433
  • [29] A novel immunotherapy for advanced melanoma.
    Wang, X
    Chen, HY
    Lin, JR
    Xie, B
    Wu, L
    Yang, DM
    [J]. CLINICAL IMMUNOLOGY, 2002, 103 (03) : S72 - S73
  • [30] Advances in immunotherapy for melanoma management
    Dany, Mohammed
    Nganga, Rose
    Chidiac, Alissar
    Hanna, Edith
    Matar, Sara
    Elston, Dirk
    [J]. HUMAN VACCINES & IMMUNOTHERAPEUTICS, 2016, 12 (10) : 2501 - 2511
12345