Wound healing

被引：535

作者：

Wang, Peng-Hui ^{[1
,2
,3
,4
]}

Huang, Ben-Shian ^{[1
,2
,3
]}

Horng, Huann-Cheng ^{[1
,2
,5
]}

Yeh, Chang-Ching ^{[1
,2
,3
]}

Chen, Yi-Jen ^{[1
,2
,3
]}

机构：

[1] Taipei Vet Gen Hosp, Dept Obstet & Gynecol, 201,Sect 2,Shi Pai Rd, Taipei 112, Taiwan

[2] Natl Yang Ming Univ, Dept Obstet & Gynecol, Taipei, Taiwan

[3] Natl Yang Ming Univ, Inst Clin Med, Taipei, Taiwan

[4] China Med Univ Hosp, Dept Med Res, Taichung, Taiwan

[5] Natl Yang Ming Univ, Inst BioMed Informat, Taipei, Taiwan

来源：

JOURNAL OF THE CHINESE MEDICAL ASSOCIATION | 2018年 / 81卷 / 02期

关键词：

Pathophysiology; Wound healing; MESENCHYMAL STEM-CELLS; INHIBITS COLLAGEN-SYNTHESIS; HYPERTROPHIC SCAR FORMATION; POSSIBLE INVOLVEMENT; KELOID FIBROBLASTS; PROSTAGLANDIN E-2; PART I; SKIN; PROLIFERATION; REGENERATION;

D O I：

10.1016/j.jcma.2017.11.002

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Wound healing is an important physiological process to maintain the integrity of skin after trauma, either by accident or by intent procedure. The normal wound healing involves three successive but overlapping phases, including hemostasis/inflammatory phase, proliferative phase, and remodeling phase. Aberration of wound healing, such as excessive wound healing (hypertrophic scar and keloid) or chronic wound (ulcer) impairs the normal physical function. A large number of sophisticated experimental studies have provided insights into wound healing. This article highlights the information after 2010, and the main text includes (i) wound healing; (ii) wound healing in fetus and adult; (iii) prostaglandins and wound healing; (iv) the pathogenesis of excessive wound healing; (v) the epidemiology of excessive wound healing; (vi) in vitro and in vivo studies for excessive wound healing; (vii) stem cell therapy for excessive wound healing; and (viii) the prevention strategy for excessive wound healing. Copyright (C) 2017, the Chinese Medical Association. Published by Elsevier Taiwan LLC.

引用

页码：94 / 101

页数：8

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