Magnetically separable sulfonic acid catalysed one-pot synthesis of diverse indole derivatives

被引:29
|
作者
Kothandapani, Jagatheeswaran [1 ]
Ganesan, Asaithampi [1 ]
Ganesan, Subramaniapillai Selva [1 ]
机构
[1] SASTRA Univ, Sch Chem & Biotechnol, Dept Chem, Thanjavur 613401, India
关键词
Diarylmethyl indole; Bioactive molecule; Iron oxide; Aminoalkylated indole; Di(indolyl)oxindole; SUSTAINABLE ORGANIC-SYNTHESIS; FRIEDEL-CRAFTS REACTIONS; FE3O4; NANOPARTICLES; MULTICOMPONENT REACTIONS; IN-VITRO; EFFICIENT; NANOCATALYST; HETEROCYCLES; ALDEHYDES;
D O I
10.1016/j.tetlet.2015.08.043
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Fe3O4-OSO3H was identified as an efficient reusable catalyst for the facile synthesis of diarylmethyl indole derivatives under neat condition by C-C bond forming reaction. Fe3O4-OSO3H catalysis was further extended to C-N bond forming reactions and for the synthesis of spermicidal 3,3'-di(indolyl)oxindole derivative. All the products were obtained in good to excellent yields. (C) 2015 Elsevier Ltd. All rights reserved.
引用
收藏
页码:5568 / 5572
页数:5
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