Smoking comorbidity in alcoholism: Neurobiological and neurocognitive consequences

被引:73
|
作者
Meyerhoff, DJ
Tizabi, Y
Staley, JK
Durazzo, TC
Glass, JM
Nixon, SJ
机构
[1] Univ Calif San Francisco, Dept Radiol, San Francisco, CA 94143 USA
[2] Dept Vet Affairs Med Ctr, San Francisco, CA USA
[3] Howard Univ, Dept Pharmacol, Washington, DC 20059 USA
[4] Yale Univ, Dept Psychiat, New Haven, CT 06520 USA
[5] Univ Michigan, Addict Res Ctr, Ann Arbor, MI 48109 USA
[6] Univ Kentucky, Dept Psychol, Lexington, KY 40506 USA
关键词
nicotine; cigarette smoking; comorbidity; neurocognition; neuroimaging;
D O I
10.1111/j.1530-0277.2006.00034.x
中图分类号
R194 [卫生标准、卫生检查、医药管理];
学科分类号
摘要
Considerable research attests to the adverse effects or chronic smoking on cardiac, pulmonary, and vascular function as well as oil increased risk for Various cancers. However, comparatively little is known about the effects or chronic smoking on brain Function. Although smoking rates have decreased in the developed world (they have increased in the developing world), smoking rates have been at a persistently high level in individual, with alcohol use disorders. Despite the high prevalence of comorbid chronic smoking and alcohol dependence, very few studies have addressed the separate and interactive effects that smoking and alcoholic drinking may have oil neurobiology and brain function. This symposium which took place at the annual meeting of the Research Society oil Alcoholism in Santa Barbara, California, oil June 29, 2005, postulates that the neurobiologic and neuro-cognitive abnormalities commonly described in studies of alcohol-dependent individuals are modulated by concurrent abuse of tobacco products and that brain recovery in abstinent alcoholic individuals is affected by chronic smoking. Four expert speakers and a discussant from different research disciplines focus in this symposium Oil the description of neurobiological and neurobehavioral effects because Of concomitant drinking and smoking. Understanding the potential separate effects and interactions of chronic nicotine/smoking and alcohol consumption promotes a better understanding of specific mechanisms and neurocognitive consequences of brain ill injury and brain recovery with abstinence. The material presented contributes useful information to ongoing discussions about treatment strategies for these comorbid disorders and valuable educational material that call be used to affect public perception about smoking and perhaps health policy.
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页码:253 / 264
页数:12
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