α-GLUCOSIDASE INHIBITORY CONSTITUENTS FROM Trichosanthis Radix

被引：0
|
作者：
Chen, Xue-Lin [1 ,2 ]
Zhang, Kun [1 ]
Ni, Ji-Yan [1 ,2 ]
Zhao, Xia [1 ]
Zhang, Yu-Mei [1 ,2 ]
机构：
[1] Chinese Acad Sci, Xishuangbanna Trop Bot Garden, Key Lab Trop Plant Resources & Sustainable Use, Kunming 650223, Yunnan, Peoples R China
[2] Univ Chinese Acad Sci, Beijing 100049, Peoples R China
来源：
CHEMISTRY OF NATURAL COMPOUNDS | 2022年 / 58卷 / 05期
关键词：
Trichosanthis Radix; hypoglycemic activities; alpha-glucosidase; CHEMICAL-CONSTITUENTS;
D O I：
10.1007/s10600-022-03800-z
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
One new compound, beta-D-apiofuranosyl-(1 -> 6)-1-ethyl-O-beta-D-glucopyranoside (1), and 11 known compounds were isolated from Trichosanthis Radix. Their structures were mainly elucidated by NMR and MS spectra. All the isolated compounds were tested for their inhibitory activities against alpha-glucosidase, and compound 11 exhibited potential inhibitory activity with an IC50 value of 36.41 +/- 0.54 mu M.
引用
收藏
页码：796 / 798
页数：3
相关论文
共 50 条
  • [1] α-Glucosidase Inhibitory Constituents from Trichosanthis Radix
    Xue-Lin Chen
    Kun Zhang
    Ji-Yan Ni
    Xia Zhao
    Yu-Mei Zhang
    [J]. Chemistry of Natural Compounds, 2022, 58 : 796 - 798
  • [2] α-glucosidase inhibitory constituents from Duranta repens
    Iqbal, K
    Malik, A
    Mukhtar, N
    Anis, I
    Khan, SN
    Choudhary, ML
    [J]. CHEMICAL & PHARMACEUTICAL BULLETIN, 2004, 52 (07) : 785 - 789
  • [3] α-Glucosidase inhibitory constituents from Chrozophora plicata
    Tabussum, Asia
    Riaz, Naheed
    Saleem, Muhammad
    Ashraf, Muhammad
    Ahmad, Maqsood
    Alam, Umber
    Jabeen, Bushra
    Malik, Abdul
    Jabbar, Abdul
    [J]. PHYTOCHEMISTRY LETTERS, 2013, 6 (04) : 614 - 619
  • [4] α-glucosidase inhibitory constituents from Toona sinensis
    Jun Zhao
    Xuan-Wei Zhou
    Xiao-Bin Chen
    Quan-Xi Wang
    [J]. Chemistry of Natural Compounds, 2009, 45 : 244 - 246
  • [5] α-glucosidase inhibitory constituents from Toona sinensis
    Zhao, Jun
    Zhou, Xuan-Wei
    Chen, Xiao-Bin
    Wang, Quan-Xi
    [J]. CHEMISTRY OF NATURAL COMPOUNDS, 2009, 45 (02) : 244 - 246
  • [6] α-Glucosidase inhibitory constituents from Cuscuta reflexa
    Anis, E
    Anis, I
    Ahmed, S
    Musiafa, G
    Malik, A
    Afza, N
    Hai, SMA
    Shahzad-Ul-Hussan, S
    Choudhary, MI
    [J]. CHEMICAL & PHARMACEUTICAL BULLETIN, 2002, 50 (01) : 112 - 114
  • [7] Effect of Radix Ginseng and Radix Trichosanthis on the melanogenesis
    Im, SJ
    Kim, KN
    Yun, YG
    Lee, JC
    Mun, YJ
    Kim, JH
    Woo, WH
    [J]. BIOLOGICAL & PHARMACEUTICAL BULLETIN, 2003, 26 (06) : 849 - 853
  • [8] Triterpenoids and α-glucosidase inhibitory constituents from Salacia hainanensis
    Yu, Mei-Hua
    Shi, Zheng-Feng
    Yu, Bang-Wei
    Pi, En-Hao
    Wang, He-Yao
    Hou, Ai-Jun
    Lei, Chun
    [J]. FITOTERAPIA, 2014, 98 : 143 - 148
  • [9] Chemical Constituents from Trichosanthis pericarpium
    Shi, Guoyu
    Xu, Meixia
    Duan, Wenjuan
    Fang, Lei
    Liu, Wei
    Wang, Xiao
    Zhang, Yongqing
    [J]. ASIAN JOURNAL OF CHEMISTRY, 2014, 26 (15) : 4626 - 4630
  • [10] Novel peptides with α-glucosidase inhibitory activity from Changii Radix hydrolysates
    Liu, Lingling
    Chen, Jianwei
    Li, Xiang
    [J]. PROCESS BIOCHEMISTRY, 2021, 111 : 200 - 206
12345