Personalized Medicine and Pediatric Asthma

被引:2
|
作者
Pajor, Nathan M. [1 ]
Guilbert, Theresa W. [2 ,3 ]
机构
[1] Cincinnati Childrens Hosp Med Ctr, Dept Pediat, 3333 Burnet Ave,MLC 7041, Cincinnati, OH 45229 USA
[2] Univ Cincinnati, Dept Pediat, Cincinnati, OH USA
[3] Cincinnati Childrens Hosp Med Ctr, Div Pulm, 3333 Burnet Ave,MLC 7041, Cincinnati, OH 45229 USA
关键词
Personalized medicine; Pediatric asthma; Biologics; Preschool; School-age; Adolescent; QUALITY-OF-LIFE; ADD-ON THERAPY; DOUBLE-BLIND; BRONCHIAL THERMOPLASTY; ALLERGIC-ASTHMA; PERSISTENT ASTHMA; CHILDHOOD ASTHMA; RANDOMIZED-TRIAL; ANTI-IGE; OMALIZUMAB;
D O I
10.1016/j.iac.2018.12.009
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
Asthma is a heterogeneous disorder described by a large number of clinical features. A growing body of literature on more specific asthma phenotypes provides evidence for a phenotype-based approach to management in which specific therapies are recommended based on patient and disease characteristics. This understanding, coupled with an increase in the number of available therapies for children with asthma, as well as emerging therapies and phenotypic markers, will allow for improved asthma management in the future.
引用
收藏
页码:221 / +
页数:13
相关论文
共 50 条
  • [41] Personalized Medicine in Allergic Asthma: At the Crossroads of Allergen immunotherapy and "Biologicals"
    Fritzsching, Benedikt
    [J]. FRONTIERS IN PEDIATRICS, 2017, 5
  • [42] Translating Asthma: Dissecting the Role of Metabolomics, Genomics and Personalized Medicine
    Andrew Bush
    [J]. The Indian Journal of Pediatrics, 2018, 85 : 643 - 650
  • [43] Recent Advances in Severe Asthma From Phenotypes to Personalized Medicine
    Schoettler, Nathan
    Strek, Mary E.
    [J]. CHEST, 2020, 157 (03) : 516 - 528
  • [44] How to apply the personalized medicine in obesity-associated asthma?
    Tiotiu, Angelica
    Labor, Marina
    Nedeva, Denislava
    Novakova, Silviya
    Oguzulgen, Ipek Kivilcim
    Mihaicuta, Stefan
    Braido, Fulvio
    [J]. EXPERT REVIEW OF RESPIRATORY MEDICINE, 2020, 14 (09) : 905 - 915
  • [45] Translating Asthma: Dissecting the Role of Metabolomics, Genomics and Personalized Medicine
    Bush, Andrew
    [J]. INDIAN JOURNAL OF PEDIATRICS, 2018, 85 (08): : 643 - 650
  • [46] Biologic therapy in asthma: entering the new age of personalized medicine
    Fajt, Merritt L.
    Wenzel, Sally E.
    [J]. JOURNAL OF ASTHMA, 2014, 51 (07) : 669 - 676
  • [47] Personalized asthma management in pediatric patients based on treatment response
    Navanandan, Nidhya
    Szefler, Stanley J.
    [J]. EXPERT REVIEW OF PRECISION MEDICINE AND DRUG DEVELOPMENT, 2020, 5 (06): : 439 - 446
  • [48] Controlling the Risk Domain in Pediatric Asthma through Personalized Care
    Anderson, William C., III
    Szefler, Stanley J.
    [J]. SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE, 2018, 39 (01) : 36 - 44
  • [49] Application of Metabolomics in Pediatric Asthma: Prediction, Diagnosis and Personalized Treatment
    Papamichael, Maria Michelle
    Katsardis, Charis
    Sarandi, Evangelia
    Georgaki, Spyridoula
    Frima, Eirini-Sofia
    Varvarigou, Anastasia
    Tsoukalas, Dimitris
    [J]. METABOLITES, 2021, 11 (04)
  • [50] Incorporating the airway microbiome into asthma phenotyping: Moving toward personalized medicine for noneosinophilic asthma
    Durack, Juliana
    Boushey, Homer A.
    Huang, Yvonne J.
    [J]. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2018, 141 (01) : 82 - 83