Photo-induced cytotoxicity of water-soluble fullerene

被引:59
|
作者
Nakajima, N [1 ]
Nishi, C [1 ]
Li, FM [1 ]
Ikada, Y [1 ]
机构
[1] KYOTO UNIV,BIOMED ENGN RES CTR,SAKYO KU,KYOTO 606,JAPAN
来源
FULLERENE SCIENCE AND TECHNOLOGY | 1996年 / 4卷 / 01期
关键词
fullerene; cytotoxicity; superoxide; superoxide dismutase;
D O I
10.1080/10641229608001533
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
The reaction of C-60 with poly(ethylene glycol) having a terminal primary amino group or a mixture of ethylene diamine and poly(ethylene glycol) having terminal carboxyl groups resulted in formation of water-soluble C-60 conjugates. These conjugates showed strong cytotoxicity to L929 cells upon visible light irradiation as a result of superoxide production.
引用
收藏
页码:1 / 19
页数:19
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