Prevalence of hypothyroidism in rheumatoid arthritis and its correlation with disease activity

被引：21
|
作者：
Joshi, Prakash [1 ]
Agarwal, Abhishek [1 ]
Vyas, Sony [1 ]
Kumar, Ravindra [2 ]
机构：
[1] Sri Aurobindo Med Coll & Post Grad Inst, Dept Med, Indore Ujjain Highway, Indore 453111, Madhya Pradesh, India
[2] Sri Aurobindo Med Coll & Post Grad Inst, Cent Res Lab, Indore, Madhya Pradesh, India
来源：
TROPICAL DOCTOR | 2017年 / 47卷 / 01期
关键词：
Autoimmune thyroid disease; disease activity score; hypothyroidism; rheumatoid arthritis (RA); THYROID-DYSFUNCTION; CLASSIFICATION; CRITERIA; RISK;
D O I：
10.1177/0049475515627235
中图分类号：
R1 [预防医学、卫生学];
学科分类号：
1004 ; 120402 ;
摘要：
Objectives To analyse the prevalence of hypothyroidism in rheumatoid arthritis (RA) patients and to elucidate its correlation with disease activity. Methods A total of 52 RA patients were enrolled in this study. All patients were assessed fully clinically and underwent routine laboratory investigation including thyroid function testing. Results Hypothyroidism (defined as having a TSH level >4.20IU/mL) was observed in 20/52 (38.4%). Erythrocyte sedimentation rates (ESR) were found significantly elevated in patients with hypothyroidism compared to those without (36.324.2 vs. 24.6 +/- 9.0mm/h). Disease activity parameters such as DAS-28-ESR, tender joint count; VAS scores were also significantly higher in the former. A significant correlation with serum TSH levels was observed with ESR and DAS-28-ESR. Conclusion Thyroid function test should be included in clinical evaluation of RA patients.
引用
收藏
页码：6 / 10
页数：5
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