Mortality statistics in England and Wales: the SARS-CoV-2 paradox

被引:3
|
作者
Harrison, Gabrielle [1 ,2 ]
Newport, Daniel [1 ,2 ]
Robbins, Tim [2 ,3 ]
Arvanitis, Theodoros N. [3 ]
Stein, Andrew [2 ]
机构
[1] Univ Warwick, Warwick Med Sch, Coventry, W Midlands, England
[2] Univ Hosp Coventry & Warwickshire, NHS Trust, Coventry, W Midlands, England
[3] Univ Warwick, WMG, Inst Digital Healthcare, Coventry CV4 7AL, W Midlands, England
基金
英国工程与自然科学研究理事会; 英国惠康基金; 英国医学研究理事会; 英国经济与社会研究理事会;
关键词
SARS-CoV-2; COVID-19; mortality rate; respiratory disease; paradox; United Kingdom;
D O I
10.1177/0300060520931298
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Objective To analyse mortality statistics in the United Kingdom during the initial phases of the severe acute respiratory coronavirus 2 (SARS-CoV-2) pandemic and to understand the impact of the pandemic on national mortality. Methods Retrospective review of weekly national mortality statistics in the United Kingdom over the past 5 years, including subgroup analysis of respiratory mortality rates. Results During the early phases of the SARS-CoV-2 pandemic in the first months of 2020, there were consistently fewer deaths per week compared with the preceding 5 years. This pattern was not observed at any other time within the past 5 years. We have termed this phenomenon the "SARS-CoV-2 paradox." We postulate potential explanations for this seeming paradox and explore the implications of these data. Conclusions Paradoxically, but potentially importantly, lower rather than higher weekly mortality rates were observed during the early stages of the SARS-CoV-2 pandemic. This paradox may have implications for current and future healthcare utilisation. A rebound increase in non-SARS-CoV-2 mortality later this year might coincide with the peak of SARS-CoV-2 admissions and mortality.
引用
收藏
页数:7
相关论文
共 50 条
  • [31] The burden and dynamics of hospital-acquired SARS-CoV-2 in England
    Cooper, Ben S.
    Evans, Stephanie
    Jafari, Yalda
    Thi Mui Pham
    Mo, Yin
    Lim, Cherry
    Pritchard, Mark G.
    Pople, Diane
    Hall, Victoria
    Stimson, James
    Eyre, David W.
    Read, Jonathan M.
    Donnelly, Christl A.
    Horby, Peter
    Watson, Conall
    Funk, Sebastian
    Robotham, Julie V.
    Knight, Gwenan M.
    [J]. NATURE, 2023, 623 (7985) : 132 - +
  • [32] Snapshot PCR surveillance for SARS-CoV-2 in hospital staff in England
    Brown, Colin S.
    Clare, Kathryn
    Chand, Meera
    Andrews, Julie
    Auckland, Cressida
    Beshir, Sarah
    Choudhry, Saher
    Davies, Kerrie
    Freeman, Jane
    Gallini, Andrew
    Moores, Rachel
    Patel, Trupti
    Poznalska, Gosia
    Rodger, Alison
    Roberts, Stella
    Rooney, Christopher
    Wilcox, Mark
    Warren, Simon
    Ellis, Joanna
    Gopal, Robin
    Dunning, Jake
    Zambon, Maria
    Hopkins, Susan
    [J]. JOURNAL OF INFECTION, 2020, 81 (03) : 427 - 434
  • [33] Detection of SARS-CoV-2 by Use of the Cepheid Xpert Xpress SARS-CoV-2 and Roche cobas SARS-CoV-2 Assays
    Moran, Angelica
    Beavis, Kathleen G.
    Matushek, Scott M.
    Ciaglia, Carol
    Francois, Nina
    Tesic, Vera
    Love, Nedra
    [J]. JOURNAL OF CLINICAL MICROBIOLOGY, 2020, 58 (08)
  • [34] Investigation of a SARS-CoV-2 Outbreak at an Automotive Manufacturing Site in England
    Raja, Amber, I
    van Veldhoven, Karin
    Ewuzie, Adanna
    Frost, Gillian
    Sandys, Vince
    Atkinson, Barry
    Nicholls, Ian
    Graham, Alice
    Higgins, Hannah
    Coldwell, Matthew
    Simpson, Andrew
    Cooke, Joan
    Bennett, Allan
    Barber, Chris
    Morgan, Derek
    Atchison, Christina
    Keen, Chris
    Fletcher, Tony
    Pearce, Neil
    Brickley, Elizabeth B.
    Chen, Yiqun
    [J]. INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, 2022, 19 (11)
  • [35] An outbreak of SARS-CoV-2 in a public-facing office in England
    Nicholls, G.
    Atkinson, B.
    van Veldhoven, K.
    Nicholls, I
    Coldwell, M.
    Clarke, A.
    Atchison, C. J.
    Raja, A., I
    Bennett, A. M.
    Morgan, D.
    Pearce, N.
    Fletcher, T.
    Brickley, E. B.
    Chen, Y.
    [J]. OCCUPATIONAL MEDICINE-OXFORD, 2023,
  • [36] The burden and dynamics of hospital-acquired SARS-CoV-2 in England
    Ben S. Cooper
    Stephanie Evans
    Yalda Jafari
    Thi Mui Pham
    Yin Mo
    Cherry Lim
    Mark G. Pritchard
    Diane Pople
    Victoria Hall
    James Stimson
    David W. Eyre
    Jonathan M. Read
    Christl A. Donnelly
    Peter Horby
    Conall Watson
    Sebastian Funk
    Julie V. Robotham
    Gwenan M. Knight
    [J]. Nature, 2023, 623 : 132 - 138
  • [37] A paradox of social distancing for SARS-CoV-2: loneliness and heightened immunological risk
    Liron Rozenkrantz
    Michael H. Bernstein
    Christopher C. Hemond
    [J]. Molecular Psychiatry, 2020, 25 : 3442 - 3444
  • [38] Diabetes associates with mortality in critically ill patients with SARS-CoV-2 pneumonia: No diabetes paradox in COVID-19
    Bellaver, Priscila
    Schneider, Larissa
    Schaeffer, Ariell F.
    Henrique, Lilian Rodrigues
    Camargo, Joiza Lins
    Gerchman, Fernando
    Leitao, Cristiane B.
    Rech, Tatiana H.
    [J]. HELIYON, 2023, 9 (08)
  • [39] Maternal Mortality with SARS-COV-2 during its 4th Wave in Pakistan: The Vaccine Paradox and Pregnancy
    Aslam, Javaria
    Masroor, Momina
    Mehmood, Qurat-ul-Ain
    Arshad, Munazza
    Jabeen, Salma
    Mushtaq, Muhammad Azam
    [J]. JCPSP-JOURNAL OF THE COLLEGE OF PHYSICIANS AND SURGEONS PAKISTAN, 2022, 32 (01): : 119 - 121
  • [40] The impact of vaccination and SARS-CoV-2 variants on the virological response to SARS-CoV-2 infections during the Alpha, Delta, and Omicron waves in England
    Lunt, Rachel
    Quinot, Catherine
    Kirsebom, Freja
    Andrews, Nick
    Skarnes, Catriona
    Letley, Louise
    Haskins, Donna
    Angel, Catriona
    Firminger, Skye
    Ratcliffe, Kay
    Rajan, Shelina
    Sherridan, Angela
    Ijaz, Samreen
    Zambon, Maria
    Brown, Kevin
    Ramsay, Mary
    Bernal, Jamie Lopez
    [J]. JOURNAL OF INFECTION, 2024, 88 (01) : 21 - 29