Fungitoxic alkaloids from Hokkaido Corydalis species

被引：55
|
作者：
Ma, WG
Fukushi, Y
Tahara, S [1 ]
机构：
[1] Hokkaido Univ, Fac Agr, Dept Appl Biosci, Kita Ku, Sapporo, Hokkaido 0608589, Japan
[2] Japan Sci & Technol Corp, CREST, Kawaguchi, Saitama 3320012, Japan
来源：
FITOTERAPIA | 1999年 / 70卷 / 03期
关键词：
fungitoxic alkaloids; plant defensive substances; Corydalis incisa; Corydalis ambigua; papaveraceae;
D O I：
10.1016/S0367-326X(99)00045-3
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Two species of the genus Corydalis (C. incisa and C, ambigua) were phytochemically studied for their fungitoxic alkaloids. Thirteen alkaloids were isolated and identified by spectroscopic methods including mass and NMR techniques. Compounds 1 (corynoline) and 2 (acetylcorynoline) were found to be the main active compounds. The new compound 3 (named coryincine) has no fungitoxic activity. Structure-activity relationships among compounds 1-3 are discussed. (C) 1999 Elsevier Science B.V. All rights reserved.
引用
收藏
页码：258 / 265
页数：8
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