Update on the Management of Gastroenteropancreatic Neuroendocrine Tumors With Emphasis on the Role of Imaging

被引:31
|
作者
Kim, Kyung Won [1 ,2 ,3 ]
Krajewski, Katherine M. [1 ]
Nishino, Mizuki [1 ]
Jagannathan, Jyothi P. [1 ]
Shinagare, Atul B. [1 ]
Tirumani, Sree Harsha [1 ]
Ramaiya, Nikhil H. [1 ]
机构
[1] Dana Farber Canc Inst, Dept Radiol, Boston, MA 02115 USA
[2] Univ Ulsan, Coll Med, Asan Med Ctr, Dept Radiol, Seoul, South Korea
[3] Univ Ulsan, Coll Med, Asan Med Ctr, Res Inst Radiol, Seoul, South Korea
基金
美国国家卫生研究院;
关键词
gastroenteropancreatic neuroendocrine tumor; guidelines; molecular targeted therapy; CLINICAL-PRACTICE GUIDELINES; CARCINOID-TUMORS; SOMATOSTATIN; METASTASIS; NEOPLASMS; DIAGNOSIS; ERA;
D O I
10.2214/AJR.12.10240
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
OBJECTIVE. The purposes of this article are to review the current management of gastroenteropancreatic neuroendocrine tumors (GEP-NETs) based on the 2012 National Comprehensive Cancer Network guidelines and to describe the role of imaging in a multidisciplinary approach. CONCLUSION. The management of GEP-NETs has become complex, requiring a multidisciplinary approach. The World Health Organization classification of GEP-NETs has been revised; the U.S. Food and Drug Administration has approved molecular targeted agents (sunitinib, everolimus) for the treatment of pancreatic NETs; and the National Comprehensive Cancer Network clinical practice guidelines have been updated.
引用
收藏
页码:811 / 824
页数:14
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