Type I (sporadic) porphyria cutanea tarda in a hemodialysis patient: A case report

被引：3

作者：

Tarwater, Kurt ^{[2
]}

Misra, Shamita ^{[3
]}

Misra, Madhukar ^{[1
,2
]}

机构：

[1] Div Nephrol, Dept Internal Med, Columbia, MO 65212 USA

[2] Div Nephrol, Columbia, MO 65212 USA

[3] Univ Missouri, Hlth Sci Ctr, Dept Family Med, Columbia, MO USA

来源：

HEMODIALYSIS INTERNATIONAL | 2008年 / 12卷

关键词：

Hemodialysis; porphyria cutanea tarda; blisters;

D O I：

10.1111/j.1542-4758.2008.00323.x

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

A hemodialysis patient with hepatitis C virus infection developed painful blisters on her hands that burst spontaneously. She was found to have serum porphyrin levels > 2000 nmol/L. A punch biopsy revealed subepidermal blistering with festooning of dermal papillae associated with a mixed inflammatory infiltrate. Based on the clinical, biochemical, and histologic findings, a diagnosis of porphyria cutanea tarda was made. Treatment was started with twice-weekly phlebotomy and oral hydroxychloroquine and significant clinical improvement resulted.

引用

页码：S38 / S42

页数：5

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