Type I (sporadic) porphyria cutanea tarda in a hemodialysis patient: A case report

被引：3
|
作者：
Tarwater, Kurt [2 ]
Misra, Shamita [3 ]
Misra, Madhukar [1 ,2 ]
机构：
[1] Div Nephrol, Dept Internal Med, Columbia, MO 65212 USA
[2] Div Nephrol, Columbia, MO 65212 USA
[3] Univ Missouri, Hlth Sci Ctr, Dept Family Med, Columbia, MO USA
来源：
HEMODIALYSIS INTERNATIONAL | 2008年 / 12卷
关键词：
Hemodialysis; porphyria cutanea tarda; blisters;
D O I：
10.1111/j.1542-4758.2008.00323.x
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
A hemodialysis patient with hepatitis C virus infection developed painful blisters on her hands that burst spontaneously. She was found to have serum porphyrin levels > 2000 nmol/L. A punch biopsy revealed subepidermal blistering with festooning of dermal papillae associated with a mixed inflammatory infiltrate. Based on the clinical, biochemical, and histologic findings, a diagnosis of porphyria cutanea tarda was made. Treatment was started with twice-weekly phlebotomy and oral hydroxychloroquine and significant clinical improvement resulted.
引用
收藏
页码：S38 / S42
页数：5
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