Cloning and sequencing of a human cDNA encoding ornithine decarboxylase antizyme inhibitor

被引:24
|
作者
Koguchi, K [1 ]
Kobayashi, S [1 ]
Hayashi, T [1 ]
Matsufuji, S [1 ]
Murakami, Y [1 ]
Hayashi, S [1 ]
机构
[1] JIKEI UNIV,SCH MED,DEPT BIOCHEM 2,MINATO KU,TOKYO 105,JAPAN
关键词
ornithine decarboxylase; ornithine decarboxylase antizyme; antizyme inhibitor; polyamine;
D O I
10.1016/S0167-4781(97)00106-1
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
We report here cloning and sequencing human antizyme inhibitor from a human kidney cDNA library. Amino acid sequence deduced from the nucleotide sequence shows 92.9% identity to that of rat antizyme inhibitor. Northern blot analysis reveals that antizyme inhibitor is expressed in human liver. (C) 1997 Elsevier Science B.V.
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页码:209 / 216
页数:8
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