nanoTRON: a Picasso module for MLP-based classification of super-resolution data

被引:11
|
作者
Auer, Alexander [1 ,2 ,3 ]
Strauss, Maximilian T. [3 ]
Strauss, Sebastian [1 ,2 ,3 ]
Jungmann, Ralf [1 ,2 ,3 ]
机构
[1] Ludwig Maximilians Univ Munchen, Dept Phys, D-80539 Munich, Germany
[2] Ludwig Maximilians Univ Munchen, Ctr Nanosci, D-80539 Munich, Germany
[3] Max Planck Inst Biochem, D-82152 Martinsried, Germany
基金
欧洲研究理事会;
关键词
DNA; MICROSCOPY; KINETICS; BINDING;
D O I
10.1093/bioinformatics/btaa154
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Motivation: Classification of images is an essential task in higher-level analysis of biological data. By bypassing the diffraction limit of light, super-resolution microscopy opened up a new way to look at molecular details using light microscopy, producing large amounts of data with exquisite spatial detail. Statistical exploration of data usually needs initial classification, which is up to now often performed manually. Results: We introduce nanoTRON, an interactive open-source tool, which allows super-resolution data classification based on image recognition. It extends the software package Picasso with the first deep learning tool with a graphic user interface.
引用
收藏
页码:3620 / 3622
页数:3
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