Focal myositis - A neurogenic phenomenon?

被引：13

作者：

Lunde, Hanne Marie Boe ^{[2
]}

Skeie, Geir Olve ^{[2
]}

Bertelsen, Anne K. ^{[2
]}

Karlsen, Bjorn ^{[2
]}

Miletic, Hrvoje ^{[3
]}

Lindal, Sigurd ^{[4
]}

Brautaset, Nils J. ^{[5
]}

Bindoff, Laurence A. ^{[1
,2
]}

机构：

[1] Univ Bergen, Dept Clin Med, N-5021 Bergen, Norway

[2] Haukeland Hosp, Dept Neurol, N-5021 Bergen, Norway

[3] Haukeland Hosp, Dept Pathol, N-5021 Bergen, Norway

[4] Univ Tromso Hosp, Dept Pathol, N-9038 Tromso, Norway

[5] Vestfold Cent Hosp, Dept Neurol, N-3103 Tonsberg, Norway

来源：

NEUROMUSCULAR DISORDERS | 2012年 / 22卷 / 04期

关键词：

Focal myositis; Denervation hypertrophy; Electromyography; Radiculopathy; DENERVATION HYPERTROPHY; REPETITIVE DISCHARGES; MUSCLE HYPERTROPHY; RADICULOPATHY; CALF; INJURY;

D O I：

10.1016/j.nmd.2011.10.023

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We report four cases of focal myositis. The patients, three men and one woman, had painful muscle hypertrophy, affecting four different sites. MRI confirmed the muscle enlargement and oedema. Electromyography revealed evidence of acute and chronic denervation in all four cases. Muscle biopsy was available in three and confirmed features suggestive of focal myositis. Based on our patient material, we suggest that chronic nerve irritation, such as compression, can lead to muscle hypertrophy which, when prolonged, provokes fibre necrosis and secondary inflammation. Our finding in four patients having hypertrophy involving four different sites, leads us further to suggest that this may be the common mechanism behind focal myositis. (C) 2011 Elsevier B.V. All rights reserved.

引用

页码：350 / 354

页数：5

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