Effectiveness of Levonorgestrel - Releasing Intrauterine System in Perimenopausal Bleeding

被引:1
|
作者
Olaru, Flavius [1 ]
Olaru, Constantin [1 ]
Olaru, Viviana [2 ]
Nussbaum, Laura [3 ]
Hogea, Lavinia [3 ]
Folescu, Roxana [4 ]
Grigoras, Mirela [4 ]
Pascu, Alina Mihaela [5 ]
Poroch, Vladimir [6 ,7 ]
Erdelean, Dragos [1 ]
机构
[1] Victor Babes Univ Med & Pharm, Dept Obstet & Gynecol, Dr D Popescu Hosp, 2 Eftimie Murgu Sq, Timisoara 300041, Romania
[2] Victor Babes Univ Med & Pharm, Dept Plast & Reparatory Surg, SCJUT, 2 Eftimie Murgu Sq, Timisoara 300041, Romania
[3] Victor Babes Univ Med & Pharm, Dept Neurosci, 2 Eftimie Murgu Sq, Timisoara 300041, Romania
[4] Victor Babes Univ Med & Pharm, Dept Anat & Embryol, 2 Eftimie Murgu Sq, Timisoara 300041, Romania
[5] Transilvania Univ Brasov, Fac Med, 29 Eroilor Blvd, Brasov 500036, Romania
[6] Grigore T Popa Univ Med & Pharm, Fac Med, 16 Univ Str, Iasi 700115, Romania
[7] Reg Inst Oncol, 2-4 G Ral Berthelot Str, Iasi 700483, Romania
来源
REVISTA DE CHIMIE | 2019年 / 70卷 / 01期
关键词
hysteroscopy; intrauterine device (IUD); Levonorgestrel (C21H28O2); menorrhagia; perimenopausal bleeding; BEHAVIOR; ETHICS; HEALTH; RISK;
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The study aimed to compare the effectiveness of conservative methods [Levonorgestrel (C21H28O2) - releasing intrauterine system (52 mg), endometrial ablation, hysteroscopy] vs. hysterectomy in perimenopausal bleeding. The study population was represented by 270 women addressed to Genesiun Clinic between 2010-2018 for perimenopausal bleeding because of different pathological circumstances: endometrial hypertrophy, polyps, uterine fibroids, endocervical lesions, chronic endometritis, intrauterine device (IUD)related pathology, congenital abnormalities. The hysteroscopy is considered the method of choice in the diagnosis/therapeutic management of hemorrhagic metropathy. The hysteroscopic surgery was superior to hysterectomy, taking into account the postoperative complications and recovery, resumption of sexual activity and working. Levonorgestrel-releasing IUS 52 mg proved safe and efficient in treating metrorrhagia associated with endometrial dysplasia, uterine fibroids, and polyps. The bipolar electrosurgical VERSAPOINT system demonstrated good results in the treatment of intrauterine pathology. Our results pointed out the alternative of a surgery a few months after the hysteroscopy and endometrial ablation, and also the possibility of repeating the hysteroscopy procedure after a while, in some cases.
引用
收藏
页码:211 / 214
页数:4
相关论文
共 50 条
  • [21] Predictive factors for failure of the levonorgestrel releasing intrauterine system in women with heavy menstrual bleeding
    Beelen, Pleun
    van den Brink, Marian J.
    Herman, Malou C.
    Geomini, Peggy M.
    Duijnhoven, Ruben G.
    Bongers, Marlies Y.
    [J]. BMC WOMENS HEALTH, 2021, 21 (01)
  • [22] Relationship between user satisfaction with the levonorgestrel-releasing intrauterine system and bleeding patterns
    Carvalho, Nelsilene M.
    Chou, Victoria
    Modesto, Waleska
    Margatho, Deborah
    Garcia, Elaine A. L.
    Bahamondes, Luis
    [J]. JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH, 2017, 43 (11) : 1732 - 1737
  • [23] Mechanism of action of the levonorgestrel-releasing intrauterine system in the treatment of heavy menstrual bleeding
    Cihangir, Uzuncakmak
    Ebru, Akbay
    Murat, Ekin
    Levent, Yasar
    [J]. INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS, 2013, 123 (02) : 146 - 149
  • [24] The levonorgestrel-releasing intrauterine system for menorrhagia
    Lewis, P
    Selvakumari, NK
    Neelapalla, S
    [J]. BRITISH JOURNAL OF HOSPITAL MEDICINE, 2006, 67 (01): : 46 - 46
  • [25] Therapeutic use of the Levonorgestrel Releasing Intrauterine System
    Taskin, Salih
    Ozmen, Batuhan
    Unlu, Cihat
    [J]. JOURNAL OF THE TURKISH-GERMAN GYNECOLOGICAL ASSOCIATION, 2006, 7 (01) : 63 - 67
  • [26] Ectopic pregnancy with levonorgestrel releasing intrauterine system
    Ojutiku, D
    Cutner, A
    Rymer, J
    [J]. BRITISH JOURNAL OF FAMILY PLANNING, 1998, 24 (02): : 85 - 86
  • [27] Usage of the levonorgestrel releasing intrauterine system in perimenopause
    Fait, Tomas
    [J]. CESKA GYNEKOLOGIE-CZECH GYNAECOLOGY, 2024, 89 (02): : 156 - 159
  • [28] Mirena - Levonorgestrel-releasing intrauterine system
    不详
    [J]. FORMULARY, 2001, 36 (02) : 93 - 93
  • [29] The levonorgestrel-releasing intrauterine system: its effect on the number of hysterectomies performed in perimenopausal women with uterine fibroids
    Machado, Rogerio Bonassi
    de Souza, Isadora Matias
    Beltrame, Amanda
    Bernardes, Carine Rejane
    Morimoto, Mariana Spagnuolo
    Santana, Narayana
    [J]. GYNECOLOGICAL ENDOCRINOLOGY, 2013, 29 (05) : 492 - 495
  • [30] The levonorgestrel intrauterine system: the benefits of reduced bleeding
    Cameron, IT
    [J]. EUROPEAN JOURNAL OF CONTRACEPTION AND REPRODUCTIVE HEALTH CARE, 2001, 6 : 27 - 32