A clear picture of renal cell carcinoma

被引:85
|
作者
Hakimi, A. Ari [1 ]
Pham, Can G. [1 ]
Hsieh, James J. [1 ]
机构
[1] Mem Sloan Kettering Canc Ctr, Human Oncol & Pathogenesis Program, New York, NY 10021 USA
关键词
KIDNEY CANCER; MUTATIONS; PBRM1; GENE; BAP1;
D O I
10.1038/ng.2708
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
Two recent studies describe the largest molecular profiling analyses to date of clear-cell renal cell carcinoma (ccRCC) and report remarkably similar findings. The recurrent pathway alterations identified in these studies open new avenues for therapeutic advances in this chemotherapy- and radiation-resistant disease.
引用
收藏
页码:849 / 850
页数:3
相关论文
共 50 条
  • [11] Clear Cell Papillary Renal Cell Carcinoma: microRNA Expression Profiling and Comparison with Clear Cell Renal Cell Carcinoma and Papillary Renal Cell Carcinoma
    Munari, E.
    Marchionni, L.
    Chitre, A.
    Hayashi, M.
    Martignoni, G.
    Brunelli, M.
    Gobbo, S.
    Argani, P.
    Allaf, M.
    Hoque, M. O.
    Netto, G. J.
    [J]. LABORATORY INVESTIGATION, 2014, 94 : 250A - 250A
  • [12] Gene expression profiling of clear cell papillary renal cell carcinoma: comparison with clear cell renal cell carcinoma and papillary renal cell carcinoma
    Fisher, Kevin E.
    Yin-Goen, Qiqin
    Alexis, Dianne
    Sirintrapun, Joseph S.
    Harrison, William
    Isett, R. Benjamin
    Rossi, Michael R.
    Moreno, Carlos S.
    Young, Andrew N.
    Osunkoya, Adeboye O.
    [J]. MODERN PATHOLOGY, 2014, 27 (02) : 222 - 230
  • [13] Clear cell papillary renal cell carcinoma: A new distinct entity or subtype of clear cell renal carcinoma
    Deml, K. -F.
    Schildhaus, H. -U.
    Comperat, E.
    Schraml, P.
    Storz, M.
    von Teichmann, A.
    Bonventre, J.
    Moch, H.
    [J]. VIRCHOWS ARCHIV, 2014, 465 : S5 - S5
  • [14] Clear Cell Papillary Renal Cell Carcinoma (CCPAP): A Distinct Entity or a Variant of Clear Cell Renal Cell Carcinoma?
    Rohan, S. M.
    Dudas, M. E.
    Gopalan, A.
    Fine, S. W.
    Reuter, V. E.
    Tickoo, S. K.
    [J]. LABORATORY INVESTIGATION, 2009, 89 : 191A - 191A
  • [15] Clear Cell Papillary Renal Cell Carcinoma (CCPAP): A Distinct Entity or a Variant of Clear Cell Renal Cell Carcinoma?
    Rohan, S. M.
    Dudas, M. E.
    Gopalan, A.
    Fine, S. W.
    Reuter, V. E.
    Tickoo, S. K.
    [J]. MODERN PATHOLOGY, 2009, 22 : 191A - 191A
  • [16] Misdiagnosis of clear cell renal cell carcinoma
    Vladimir A. Valera
    Maria J. Merino
    [J]. Nature Reviews Urology, 2011, 8 : 321 - 333
  • [17] Biomarkers in clear cell renal cell carcinoma
    George, Saby
    Bukowski, Ronald M.
    [J]. EXPERT REVIEW OF ANTICANCER THERAPY, 2007, 7 (12) : 1737 - 1747
  • [18] Misdiagnosis of clear cell renal cell carcinoma
    Valera, Vladimir A.
    Merino, Maria J.
    [J]. NATURE REVIEWS UROLOGY, 2011, 8 (06) : 321 - 333
  • [19] Clear Cell Papillary Renal Cell Carcinoma
    Zhao, Jianping
    Eyzaguirre, Eduardo
    [J]. ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE, 2019, 143 (09) : 1154 - 1158
  • [20] CLEAR CELL PAPILLARY RENAL CELL CARCINOMA
    Joseph, Keva
    Liu, Kai-Wen
    Chang, I-Wei
    [J]. POLISH JOURNAL OF PATHOLOGY, 2015, 66 (02) : 202 - 205