High-resolution MR imaging in mice

Due to its high temporal and spatial resolution, the described MR technique is able to face the requirements of the small sized, fast beating mouse heart, resulting in time-resolved visualization of the cardiac morphology and function in great detail. This allows for accurate and reproducible quantification of LV performance including wall motion and contraction-relaxation dynamics. Hence, MRI offers the non-invasive investigation of physiological and pathophysiological changes of cardiac function over time, both under acute and chronic myocardial stress.