Discovery of a potent, selective and orally active 5-HT6 receptor agonist, WAY-181187

被引：0
|
作者：
Cole, DC
Stock, JR
Lennox, WJ
Bernotas, RC
Ellingboe, JW
Leung, L
Smith, D
Zhang, GM
Li, P
Qian, L
Dawson, LA
Boikess, S
Rosenzweig-Lipson, S
Beyer, CE
Schechter, LE
机构：
[1] Wyeth Res, Chem & Screening Sci, Pearl River, NY 10965 USA
[2] Wyeth Res, Dept Drug Safety & Metab, Pearl River, NY 10965 USA
[3] Wyeth Res, Neurosci, Pearl River, NY 10965 USA
来源：
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY | 2005年 / 230卷
关键词：
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
17-MEDI
引用
收藏
页码：U2510 / U2511
页数：2
相关论文
共 50 条
  • [41] Amino aryl sulfonamides as novel and potent 5-ht6 receptor ligands
    Nirogi, Ramakrishna
    Kambhampati, Ramasastry
    Bandyala, Trinathreddy
    Konda, Jagadishbabu
    Arepalli, Sobhanadri
    Reballi, Veena
    Kothmirkar, Prabhakar
    Pamuleti, Narasimhareddy G.
    Shinde, Anil
    [J]. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2010, 240
  • [42] Tetrahydrocarbazole derivatives as novel and selective 5-HT6 receptor ligands
    Konda, Jagadishbabu
    Kambhampati, Ramasastry
    Kothmirkar, Prabhakar
    Arepalli, Sobhanadri
    Bandyala, Trinath Reddy
    Gudla, Parandhama
    Shinde, Anil K.
    Nirogi, Ramakrishna
    [J]. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2009, 238
  • [43] Substituted aminomethyl indoles: Selective 5-HT6 receptor ligands
    Nirogi, Ramakrishna V. S.
    Deshpande, Amol D.
    Daulatabad, Sarika A.
    Daulatabad, Anand V.
    Kambhampati, Rama S.
    Shirsath, Vikas S.
    [J]. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2006, 231
  • [44] MEDI 43-Aminoalkyl indoles: Novel, potent and highly selective 5-HT6 receptor antagonists
    Shinde, Anil K.
    Deshpande, Amol D.
    Chindhe, Anil K.
    Badange, Rajesh Kumar
    Karuturi, Kameswara R.
    Gangadasari, Narasimha Reddy P.
    Katta, Raja Rajeswari
    Nirogi, Ramakrishna V. S.
    [J]. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2007, 234
  • [45] RS-39604 - A POTENT, SELECTIVE AND ORALLY-ACTIVE 5-HT4 RECEPTOR ANTAGONIST
    HEGDE, SS
    BONHAUS, DW
    JOHNSON, LG
    LEUNG, E
    CLARK, RD
    EGLEN, RM
    [J]. BRITISH JOURNAL OF PHARMACOLOGY, 1995, 115 (06) : 1087 - 1095
  • [46] Identification of 3-sulfonylindazole derivatives as potent and selective 5-HT6 antagonists
    Liu, Kevin G.
    Robichaud, Albert J.
    Greenfield, Alexander A.
    Lo, Jennifer R.
    Grosanu, Cristina
    Mattes, James F.
    Cai, Yanxuan
    Zhang, Guo Ming
    Zhang, Jean Y.
    Kowal, Dianne M.
    Smith, Deborah L.
    Di, Li
    Kerns, Edward H.
    Schechter, Lee E.
    Comery, Thomas A.
    [J]. BIOORGANIC & MEDICINAL CHEMISTRY, 2011, 19 (01) : 650 - 662
  • [47] 1-Sulfonyl-6-Piperazinyl-7-Azaindoles as potent and pseudo-selective 5-HT6 receptor antagonists
    Fabritius, Charles-Henry
    Pesonen, Ullamari
    Messinger, Josef
    Horvath, Raymond
    Salo, Harri
    Galezowski, Michal
    Galek, Mariusz
    Stefanska, Klaudia
    Szeremeta-Spisak, Joanna
    Olszak-Plachta, Marta
    Buda, Anna
    Adamczyk, Justyna
    Krol, Marcin
    Prusis, Peteris
    Sieprawska-Lupa, Magdalena
    Mikulski, Maciej
    Kuokkanen, Katja
    Chapman, Hugh
    Obuchowicz, Radoslaw
    Korjamo, Timo
    Jalava, Niina
    Nowak, Mateusz
    [J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2016, 26 (11) : 2610 - 2615
  • [48] Discovery of a potent, orally available, and isoform-selective retinoic acid β2 receptor agonist
    Lund, BW
    Piu, F
    Gauthier, NK
    Eeg, A
    Currier, E
    Sherbukhin, V
    Brann, MR
    Hacksell, T
    Olsson, R
    [J]. JOURNAL OF MEDICINAL CHEMISTRY, 2005, 48 (24) : 7517 - 7519
  • [49] The 5-HT6 receptor agonist EMD 386088 promotes cognitive flexibility in rats
    Rafa, D.
    Nikiforuk, A.
    [J]. EUROPEAN NEUROPSYCHOPHARMACOLOGY, 2012, 22 : S205 - S206
  • [50] QUATERNIZED RENZAPRIDE AS A POTENT AND SELECTIVE 5-HT4 RECEPTOR AGONIST
    BAXTER, GS
    BOYLAND, P
    GASTER, LM
    KING, FD
    [J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1993, 3 (04) : 633 - 634
12345