Functionalized DNA Nanostructures for Nanomedicine

被引：7
|
作者：
Liu, Xiaowei [1 ]
Liu, Yan [1 ]
Yan, Hao [1 ]
机构：
[1] Arizona State Univ, Dept Chem & Biochem, Biodesign Inst, Tempe, AZ 85287 USA
来源：
ISRAEL JOURNAL OF CHEMISTRY | 2013年 / 53卷 / 08期
基金：
美国国家科学基金会;
关键词：
disease treatment; DNA; molecular devices; nanomedicine; nanostructures; CROSSOVER COMPLEXES; ORIGAMI STRUCTURES; DRUG-RESISTANCE; CANCER-CELLS; LOGIC GATES; PH CHANGES; APTAMERS; DELIVERY; ARRAYS; NANOPARTICLES;
D O I：
10.1002/ijch.201300002
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
DNA nanotechnology utilizes synthetic DNA strands as the building material to construct nanoscale devices, and the field has developed rapidly over the past decade. Recently, the use of DNA nanostructures for various applications, particularly biomedical ones, has drawn great interest. This review focuses on the most recent research directed at utilizing functionalized DNA devices for nanomedical applications and presents representative research progress in disease diagnosis, treatment and prevention. In addition, the safety and future clinical applications of DNA nanostructures are discussed.
引用
收藏
页码：555 / 566
页数：12
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