Catalyst free approach to benzimidazoles using air as the oxidant at room temperature

被引:69
|
作者
Zhang, Chun [1 ]
Zhang, Liangren [1 ]
Jiao, Ning [1 ,2 ]
机构
[1] Peking Univ, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Beijing 100191, Peoples R China
[2] Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China
基金
美国国家科学基金会;
关键词
METAL-FREE DIAMINATION; ONE-POT SYNTHESIS; 2-SUBSTITUTED BENZIMIDAZOLES; HETEROGENEOUS CATALYST; EFFICIENT; BENZOXAZOLES; ACTIVATION; INHIBITORS; DISCOVERY; ALKENE;
D O I
10.1039/c2gc36416f
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A green and practical method to construct benzimidazoles, which are ubiquitous structural units in a number of biologically active compounds, has been developed. The catalyst and additive free conditions, using air as oxidant and the mild conditions make this transformation very green, practical, and attractive.
引用
收藏
页码:3273 / 3276
页数:4
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