Grading cervical cord damage in neuromyelitis optica and MS by diffusion tensor MRI

被引:49
|
作者
Benedetti, B.
Valsasina, P.
Judica, E.
Martinelli, V.
Ghezzi, A.
Capra, R.
Bergamaschi, R.
Comi, G.
Filippi, M.
机构
[1] Univ Ospedale Raffaele, Neuroimaging Res Unit, Dept Neurol, Inst Sci, I-20132 Milan, Italy
[2] Osped Gallarate, Multiple Sclerosis Ctr, Gallarate, Italy
[3] Univ Brescia, Dept Neurol, Spedali Civili, Brescia, Italy
[4] Univ Pavia, Sci Inst C Mondino, Dept Neurol Sci, I-27100 Pavia, Italy
关键词
D O I
10.1212/01.wnl.0000223637.65208.7c
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The authors assessed the ability of diffusion tensor MRI to grade cervical cord damage in 10 patients with neuromyelitis optica, 10 patients with multiple sclerosis, and 10 healthy controls. The three groups differed in terms of average mean diffusivity (p = 0.008) and average fractional anisotropy (p = 0.04). There was a correlation between the Expanded Standard Disability Status Scale score and cord average mean diffusivity (r = 0.52, p = 0.02).
引用
收藏
页码:161 / 163
页数:3
相关论文
共 50 条
  • [21] Evidence for cervical cord tissue disorganisation with aging by diffusion tensor MRI
    Agosta, Federica
    Lagana, Marcella
    Valsasina, Paola
    Sala, Stefania
    Dall'Occhio, Luca
    Sormani, Maria P.
    Judica, Elda
    Filippi, Massimo
    [J]. NEUROIMAGE, 2007, 36 (03) : 728 - 735
  • [22] Diffusion tensor MRI of the cervical cord in a patient with syringomyelia and multiple sclerosis
    Agosta, F
    Rovaris, M
    Benedetti, B
    Valsasina, P
    Filippi, M
    Comi, G
    [J]. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2004, 75 (11): : 1647 - 1647
  • [23] Diffusion tensor imaging in the assessment of normal-appearing brain tissue damage in relapsing neuromyelitis optica
    Yu, C. S.
    Lin, F. C.
    Li, K. C.
    Jiang, T. Z.
    Zhu, C. Z.
    Qin, W.
    Sun, H.
    Chan, P.
    [J]. AMERICAN JOURNAL OF NEURORADIOLOGY, 2006, 27 (05) : 1009 - 1015
  • [24] Cervical cord is vulnerable to aging: A diffusion-tensor MRI study
    Valsasina, Paola
    Agosta, Federica
    Sala, Stefania
    Lagana, Marcella
    Benedetti, Beatrice
    Dall Occhio, Luca
    Sormani, Maria Pia
    Filippi, Massimo
    [J]. NEUROLOGY, 2007, 68 (12) : A308 - A309
  • [25] MRI and magnetization transfer imaging changes in the brain and cervical cord of patients with Devic's neuromyelitis optica
    Filippi, M
    Rocca, MA
    Moiola, L
    Martinelli, V
    Ghezzi, A
    Capra, R
    Salvi, F
    Comi, G
    [J]. NEUROLOGY, 1999, 53 (08) : 1705 - 1710
  • [26] A diffusion-tensor MRI study of the cervical cord damage in benign and secondary progressive multiple sclerosis patients
    Rovaris, M.
    Benedetti, B.
    Pulizzi, A.
    Caputo, D.
    Zaffaroni, M.
    Capra, R.
    Bertolotto, A.
    Martinelli, V.
    Comi, G.
    Filippi, M.
    [J]. JOURNAL OF NEUROLOGY, 2008, 255 : 53 - 53
  • [27] Assessing "occult'' cervical cord damage in patients with neuropsychiatric systemic lupus erythematosus using diffusion tensor MRI
    Benedetti, Beatrice
    Rovaris, Marco
    Judica, Elda
    Donadoni, Giovanni
    Ciboddo, Gianfranco
    Filippi, Massimo
    [J]. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2007, 78 (08): : 893 - 895
  • [28] Pathogenesis of normal-appearing white matter damage in neuromyelitis optica: Diffusion-tensor MR imaging
    Yu, Chunshui
    Lin, Fuchun
    Li, Kuncheng
    Jiang, Tianzi
    Qin, Wen
    Sun, Hong
    Chan, Piu
    [J]. RADIOLOGY, 2008, 246 (01) : 222 - 228
  • [29] Quantification of cervical cord pathology in patients with Devic's neuromyelitis optica
    Judica, E
    Benedetti, B
    Martinelli, V
    Ghezzi, A
    Capra, R
    Comi, G
    Filippi, M
    [J]. MULTIPLE SCLEROSIS, 2005, 11 : S58 - S58
  • [30] Diffusion tensor MRI of the cervical cord as a tool to monitor disease progression in ALS
    Agosta, Federica
    Valsasina, Paola
    Sala, Stefania
    Caputo, Domenico
    Perini, Michele
    Prelle, Alessandro
    Fruguglietti, Elisa
    Salvi, Fabrizio
    Bartolomei, Ilaria
    Filippi, Massimo
    [J]. NEUROLOGY, 2008, 70 (11) : A195 - A195