Grading cervical cord damage in neuromyelitis optica and MS by diffusion tensor MRI

被引:49
|
作者
Benedetti, B.
Valsasina, P.
Judica, E.
Martinelli, V.
Ghezzi, A.
Capra, R.
Bergamaschi, R.
Comi, G.
Filippi, M.
机构
[1] Univ Ospedale Raffaele, Neuroimaging Res Unit, Dept Neurol, Inst Sci, I-20132 Milan, Italy
[2] Osped Gallarate, Multiple Sclerosis Ctr, Gallarate, Italy
[3] Univ Brescia, Dept Neurol, Spedali Civili, Brescia, Italy
[4] Univ Pavia, Sci Inst C Mondino, Dept Neurol Sci, I-27100 Pavia, Italy
关键词
D O I
10.1212/01.wnl.0000223637.65208.7c
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The authors assessed the ability of diffusion tensor MRI to grade cervical cord damage in 10 patients with neuromyelitis optica, 10 patients with multiple sclerosis, and 10 healthy controls. The three groups differed in terms of average mean diffusivity (p = 0.008) and average fractional anisotropy (p = 0.04). There was a correlation between the Expanded Standard Disability Status Scale score and cord average mean diffusivity (r = 0.52, p = 0.02).
引用
收藏
页码:161 / 163
页数:3
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