Heterogeneity of corticotropin-releasing factor (CRF)

被引：2
|
作者：
Yasuda, N
Nakamura, K
机构：
[1] 2nd Department of Physiology, Iwate Medical University
[2] 2nd Department of Physiology, Iwate Medical University, Morioka 020
来源：
JAPANESE JOURNAL OF PHYSIOLOGY | 1997年 / 47卷 / 02期
关键词：
CRH; ACTH; heterogeneity; placenta; tissue CRF;
D O I：
10.2170/jjphysiol.47.147
中图分类号：
Q4 [生理学];
学科分类号：
071003 ;
摘要：
Although CRH is the major contributor to the physiological regulation of ACTH secretion, it must be recognized that a considerable degree of heterogeneity exists regarding the chemistry and biological activity of various CRF-active substances, some of which still remain to be fully clarified. The widespread extrahypothalamic sources and diverse extrapituitary actions of CRFs suggest that multiple CRF components must act in concert for the organism to cope with the environmental changes and stresses.
引用
收藏
页码：147 / 159
页数：13
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