TOMM40 Association With Alzheimer Disease Tales of APOE and Linkage Disequilibrium

被引：21
|
作者：
Guerreiro, Rita J. [1 ]
Hardy, John [1 ]
机构：
[1] UCL Inst Neurol, Reta Lilla Weston Labs, Dept Mol Neurosci, London WC1N 3BG, England
来源：
ARCHIVES OF NEUROLOGY | 2012年 / 69卷 / 10期
基金：
英国医学研究理事会;
关键词：
APOLIPOPROTEIN-E; GENETIC-VARIATION; ONSET; ALLELE; EXPRESSION; LENGTH; LOCUS; AGE;
D O I：
10.1001/archneurol.2012.1935
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
引用
收藏
页码：1243 / 1244
页数：2
相关论文
共 50 条
  • [41] DNA methylation of TOMM40-APOE-APOC2 in Alzheimer’s disease
    Yvonne Shao
    McKenzie Shaw
    Kaitlin Todd
    Maria Khrestian
    Giana D’Aleo
    P. John Barnard
    Jeff Zahratka
    Jagan Pillai
    Chang-En Yu
    C. Dirk Keene
    James B. Leverenz
    Lynn M. Bekris
    [J]. Journal of Human Genetics, 2018, 63 : 459 - 471
  • [42] Biochemical Studies of Poly-T Variants in the Alzheimer's Disease Associated TOMM40 Gene
    Hedskog, Louise
    Brohede, Jesper
    Wiehager, Birgitta
    Pinho, Catarina Moreira
    Revathikumar, Priya
    Lilius, Lena
    Glaser, Elzbieta
    Graff, Caroline
    Karlstrom, Helena
    Ankarcrona, Maria
    [J]. JOURNAL OF ALZHEIMERS DISEASE, 2012, 31 (03) : 527 - 536
  • [43] Protective association of the ε2/ε3 heterozygote with Alzheimer's disease is strengthened by TOMM40-APOE variants in men
    Kulminski, Alexander M.
    Philipp, Ian
    Loika, Yury
    He, Liang
    Culminskaya, Irina
    [J]. ALZHEIMERS & DEMENTIA, 2021, 17 (11) : 1779 - 1787
  • [44] Cerebrospinal fluid cortisol concentrations in healthy elderly are affected by both APOE and TOMM40 variants
    Bruno, Davide
    Nierenberg, Jay J.
    Ritchie, James C.
    Lutz, Michael W.
    Pomara, Nunzio
    [J]. PSYCHONEUROENDOCRINOLOGY, 2012, 37 (03) : 366 - 371
  • [45] TOMM40′523 variant and cognitive decline in older persons with APOE ε3/3 genotype
    Yu, Lei
    Lutz, Michael W.
    Wilson, Robert S.
    Burns, Daniel K.
    Roses, Allen D.
    Saunders, Ann M.
    Gaiteri, Chris
    De Jager, Philip L.
    Barnes, Lisa L.
    Bennett, David A.
    [J]. NEUROLOGY, 2017, 88 (07) : 661 - 668
  • [46] The Biological Foundation of the Genetic Association of TOMM40 with Late-onset Alzheimer's disease (vol 1863, pg 2973, 2017)
    Zietlow, Kahli
    Charalambous, Lefko
    Ng, Isaac
    Gagrani, Sonal
    Mihovilovic, Mirta
    Luo, Shuhong
    Rock, Daniel L.
    Saunders, Ann
    Roses, Allen D.
    Gottschalk, W. Kirby
    [J]. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 2018, 1864 (04): : 1216 - 1216
  • [47] TOMM40 polymorphism is associated with cerebral β-amyloid load and clinical pathology in Alzheimer's disease dementia
    Schulz, J.
    Yousaf, T.
    Oshodin, J.
    Politis, M.
    [J]. EUROPEAN JOURNAL OF NEUROLOGY, 2019, 26 : 271 - 271
  • [48] A GENOME-WIDE ASSOCIATION STUDY OF COGNITIVE DECLINE SHOWS TWO INDEPENDENT SIGNALS IN THE APOE/TOMM40 REGION.
    Zhang, Chenan
    Pierce, Brandon
    [J]. AMERICAN JOURNAL OF EPIDEMIOLOGY, 2013, 177 : S98 - S98
  • [49] Commentary on Functional analysis of APOE Locus genetic variation implicates regional enhancers in the regulation of both TOMM40 and APOE
    Carrasquillo, Minerva M.
    Morgan, Kevin
    [J]. JOURNAL OF HUMAN GENETICS, 2012, 57 (01) : 3 - 4
  • [50] TOMM40 Alterations in Alzheimer's Disease Over a 2-Year Follow-Up Period
    Goh, Liang Kee
    Lim, Wee Shiong
    Teo, Stephanie
    Vijayaraghavan, Aadhitthya
    Chan, Mark
    Tay, Laura
    Ng, Tze Pin
    Tan, Chay Hoon
    Lee, Tih Shih
    Chong, Mei Sian
    [J]. JOURNAL OF ALZHEIMERS DISEASE, 2015, 44 (01) : 57 - 61
12345