Management of Ovarian and Testicular Sex Cord-stromal Tumors in Children and Adolescents

被引：28
|
作者：
Schultz, Kris Ann P. [1 ]
Schneider, Dominik T. [2 ]
Pashankar, Farzana [3 ]
Ross, Jonathan [4 ]
Frazier, Lindsay [5 ]
机构：
[1] Childrens Hosp & Clin Minnesota, Minneapolis, MN 55404 USA
[2] Klinikum Dortmund, Dortmund, Germany
[3] Yale Univ, New Haven, CT USA
[4] Rainbow Babies & Childrens Hosp, Univ Hosp, Cleveland, OH 44106 USA
[5] Dana Farber Canc Inst, Boston, MA 02115 USA
来源：
JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY | 2012年 / 34卷
关键词：
ovarian neoplasms; testicular neoplasms; DICER1; sex cord stromal tumors; Sertoli-Leydig; juvenile granulosa cell tumor; genetics; GRANULOSA-CELL TUMOR; BLEOMYCIN COMBINATION CHEMOTHERAPY; DICER1; MUTATIONS; PARATESTICULAR TUMORS; TESTIS TUMORS; CISPLATIN; ETOPOSIDE; MARKER; VINBLASTINE; THERAPY;
D O I：
10.1097/MPH.0b013e31824e3867
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Pediatric ovarian and testicular sex cord-stromal tumors are distinct from germ cell neoplasms and may present with palpable mass or signs of hormone production. Both may be associated with specific genetic syndromes. Staging for ovarian sex cord-stromal tumors is based on the International Federation of Gynecology and Obstetrics classification for ovarian carcinoma. Treatment for those with high risk disease includes multiagent chemotherapy. Testicular stromal tumors often, though not always, follow a benign course. Additional research will help to define optimal treatment strategies for children with these rare tumors.
引用
收藏
页码：S55 / S63
页数：9
相关论文
共 50 条
  • [31] IMMUNOREACTIVE BETA-ENDORPHIN IN OVARIAN SEX CORD-STROMAL TUMORS
    OMAR, RA
    ELTABBAKH, GH
    [J]. ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE, 1987, 111 (05) : 436 - 439
  • [32] OVARIAN SEX CORD-STROMAL TUMORS - PROBLEMS IN DIFFERENTIAL-DIAGNOSIS
    YOUNG, RH
    SCULLY, RE
    [J]. PATHOLOGY ANNUAL, 1988, 23 : 237 - 296
  • [33] OVARIAN SEX CORD-STROMAL TUMORS - RECENT ADVANCES AND CURRENT STATUS
    YOUNG, RH
    SCULLY, RE
    [J]. CLINICS IN OBSTETRICS AND GYNAECOLOGY, 1984, 11 (01): : 93 - 134
  • [34] Efficacy and Safety of Bevacizumab in Recurrent Sex Cord-Stromal Ovarian Tumors
    Brown, Jubilee
    Brady, William E.
    Schink, Julian
    Van Le, Linda
    Leitao, Mario
    Yamada, S. Diane
    de Geest, Koen
    Gershenson, David M.
    [J]. CANCER, 2014, 120 (03) : 344 - 351
  • [35] Immunohistochemical Characterization of Nonhuman Primate Ovarian Sex Cord-Stromal Tumors
    Durkes, A.
    Garner, M.
    Juan-Salles, C.
    Ramos-Vara, J.
    [J]. VETERINARY PATHOLOGY, 2012, 49 (05) : 834 - 838
  • [36] Germline APC Alterations May Predispose to Testicular Sex Cord-Stromal Tumors
    Siegmund, Stephanie
    Ricci, Costantino
    Kao, Chia-Sui
    Sangoi, Ankur R.
    Mohanty, Sambit
    Fletcher, Christopher D. M.
    Colecchia, Maurizio
    Acosta, Andres M.
    [J]. AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2023, 47 (12) : 1432 - 1437
  • [37] Role of adjuvant chemotherapy in the management of ovarian non-granulosa sex cord-stromal tumors
    Nasioudis, D.
    Frey, M. K.
    Chapman-Davis, E.
    Caputo, T. A.
    Witkin, S. S.
    Holcomb, K. M.
    [J]. GYNECOLOGIC ONCOLOGY, 2018, 149 : 189 - 189
  • [38] Laparoscopical management ovarian early sex cord-stromal tumors in postmenopausal women: A proposal method
    Tinelli A.
    Pellegrino M.
    Malvasi A.
    Lorusso V.
    [J]. Archives of Gynecology and Obstetrics, 2011, 283 (Suppl 1) : S87 - S91
  • [39] Secondary cytoreductive surgery: A key tool in the management of recurrent ovarian sex cord-stromal tumors
    Namaky, D.
    Ramirez, P.
    Munsell, M.
    Nick, A.
    Gershenson, D.
    Brown, J.
    [J]. GYNECOLOGIC ONCOLOGY, 2011, 121 (01) : S40 - S40
  • [40] Does RPLND have a curative role for sex cord-stromal testicular tumors?
    Mosharafa, AA
    Foster, RS
    Bihrle, R
    Koch, MO
    Einhorn, LH
    Donohue, JP
    [J]. JOURNAL OF UROLOGY, 2002, 167 (04): : 155 - 155
12345