Fetal Surgery for Myelomeningocele

被引：23

作者：

Saadai, Payam ^{[1
]}

Farmer, Diana L. ^{[2
]}

机构：

[1] Univ Calif San Francisco, Dept Surg, Div Pediat Surg, Fetal Treatment Ctr, San Francisco, CA 94143 USA

[2] Univ Calif Davis, Sch Med, Childrens Hosp, UC Davis Hlth Syst,Div Pediat Surg,Dept Surg, Sacramento, CA 95817 USA

来源：

CLINICS IN PERINATOLOGY | 2012年 / 39卷 / 02期

关键词：

Fetal surgery; Hydrocephalus; Myelomeningocele; Neural tube defect; Shunt; Spina bifida; Ventriculomegaly; SHUNT-DEPENDENT HYDROCEPHALUS; ALLOWS NORMAL DEVELOPMENT; SPINAL-CORD-INJURY; IN-UTERO REPAIR; UNITED-STATES; MODEL; SHEEP; BIFIDA; SKIN; COMPLICATIONS;

D O I：

10.1016/j.clp.2012.04.003

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Myelomeningocele (MMC) is a congenital neural tube defect that occurs in approximately 1 in 2900 live births in the United States. It is a devastating disability with significant morbidity and mortality within the first few decades of life. MMC was the first nonlethal disease to be considered and studied for fetal surgery and is now the most common open fetal surgery performed. The recently completed MOMS randomized controlled trial has shown that fetal repair for MMC can improve hydrocephalus and hindbrain herniation, can reduce the need for vetriculoperitoneal shunting, and may improve distal neurologic function in some patients.

引用

页码：279 / +

页数：11

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