Milk fat globule membrane - a source of polar lipids for colon health? A review

被引：33
|
作者：
Kuchta, Anna M. [1 ,2 ]
Kelly, Philip M. [3 ]
Stanton, Catherine [1 ]
Devery, Rosaleen A. [4 ]
机构：
[1] TEAGASC, Moorepk Food Res Ctr, Food BioSci Dept, Fermoy, Cork, Ireland
[2] Dublin City Univ, Sch Biotechnol, Dublin 9, Ireland
[3] TEAGASC, Moorepk Food Res Ctr, Food Proc & Funct Dept, Fermoy, Cork, Ireland
[4] Dublin City Univ, Natl Inst Cellular Biotechnol, Dublin 9, Ireland
来源：
INTERNATIONAL JOURNAL OF DAIRY TECHNOLOGY | 2012年 / 65卷 / 03期
关键词：
Milk fat globule membrane; Colon cancer; Phospholipids; Sphingolipids; INTESTINAL ALKALINE SPHINGOMYELINASE; NECROSIS-FACTOR-ALPHA; ACID-BINDING PROTEIN; BREAST-CANCER CELLS; EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS; 1,2-DIMETHYLHYDRAZINE-TREATED CF1 MICE; MYELIN OLIGODENDROCYTE GLYCOPROTEIN; FAMILIAL ADENOMATOUS POLYPOSIS; CHOLINE KINASE-ACTIVITY; ABERRANT CRYPT FOCI;
D O I：
10.1111/j.1471-0307.2011.00759.x
中图分类号：
TS2 [食品工业];
学科分类号：
0832 ;
摘要：
The milk fat globule membrane (MFGM) surrounds fat globules, protects them against lipolysis and disperses the milk fat in the milk plasma. Besides their structural and emulsifying roles, in vivo and in vitro studies have demonstrated that phospholipids and sphingolipids of MFGM possess cancer risk-reducing properties. Several reports attribute its chemopreventive activity to products of sphingomyelin hydrolysis, which affect multiple cellular targets that control cell growth, differentiation and apoptosis. With knowledge on the potential health benefits of MFGM lipids and proteins, dairy industries could in the future address their research in developing new functional dairy products enriched in beneficial MFGM components.
引用
收藏
页码：315 / 333
页数：19
相关论文
共 50 条
  • [21] Healthy Breastfeeding Infants Consume Different Quantities of Milk Fat Globule Membrane Lipids
    George, Alexandra D.
    Gay, Melvin C. L.
    Selvalatchmanan, Jayashree
    Torta, Federico
    Bendt, Anne K.
    Wenk, Markus R.
    Murray, Kevin
    Wlodek, Mary E.
    Geddes, Donna T.
    [J]. NUTRIENTS, 2021, 13 (09)
  • [22] SOURCE AND SIGNIFICANCE OF LYSOSOMAL ENZYMES IN BOVINE MILK-FAT GLOBULE MEMBRANE
    ANDERSON, M
    [J]. JOURNAL OF DAIRY SCIENCE, 1977, 60 (08) : 1217 - 1222
  • [23] Effect of washing conditions on the recovery of milk fat globule membrane proteins during the isolation of milk fat globule membrane from milk
    Le, T. T.
    Van Camp, J.
    Rombaut, R.
    van Leeckwyck, F.
    Dewettinck, K.
    [J]. JOURNAL OF DAIRY SCIENCE, 2009, 92 (08) : 3592 - 3603
  • [24] CHARACTERISTICS OF FAT GLOBULE MEMBRANE OF COWS MILK
    SWOPE, FC
    BRUNNER, JR
    [J]. JOURNAL OF DAIRY SCIENCE, 1970, 53 (06) : 691 - &
  • [25] GLYCOSAMINOGLYCANS OF FAT GLOBULE MEMBRANE OF COW MILK
    LIS, D
    MONIS, B
    [J]. JOURNAL OF SUPRAMOLECULAR STRUCTURE, 1978, 8 (02): : 173 - 176
  • [26] GLYCOPROTEINS OF FAT GLOBULE MEMBRANE OF COW MILK
    VALENTICH, MA
    MONIS, B
    [J]. FEDERATION PROCEEDINGS, 1978, 37 (03) : 909 - 909
  • [27] Bioactivity of milk fat globule membrane proteins
    Rasmussen, Jan Trige
    [J]. AUSTRALIAN JOURNAL OF DAIRY TECHNOLOGY, 2009, 64 (01) : 63 - 67
  • [28] The Immunological Role of Milk Fat Globule Membrane
    Cavaletto, Maria
    Givonetti, Annalisa
    Cattaneo, Chiara
    [J]. NUTRIENTS, 2022, 14 (21)
  • [29] Comprehensive review of milk fat globule membrane proteins across mammals and lactation periods in health and disease
    Wang, Ying
    Wu, Junrui
    Zhang, Henan
    Yang, Xujin
    Gu, Ruixia
    Liu, Yumeng
    Wu, Rina
    [J]. CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION, 2024,
  • [30] Structural aspects of the milk fat globule membrane
    Smoczynski, Michal
    [J]. MEDYCYNA WETERYNARYJNA-VETERINARY MEDICINE-SCIENCE AND PRACTICE, 2014, 70 (04): : 214 - 218
12345