SYNTHESIS OF SOME ISOXAZOLE DERIVATIVES AS ANTIMICROBIAL AGENTS

被引：0
|
作者：
Sulakshana, M. [2 ]
Reddy, V. V. Narayan [1 ]
Jyostna, T. Saritha [2 ]
Reddy, K. Ramsubba [2 ]
机构：
[1] Indian Inst Chem Technol, Organ Chem Div 2, Hyderabad 500007, Andhra Pradesh, India
[2] SN Vanitha Pharm Mahavidyalaya, Dept Chem, Hyderabad 500001, Andhra Pradesh, India
来源：
INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY | 2012年 / 22卷 / 01期
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中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A new series of 5-phenyl-3-isoxazole carboxamides (4a-j) have been synthesized by reacting 5-phenyl-3-isoxazole carboxylate with various amines. These compounds have been characterized by the spectral data and evaluated for antimicrobial activity against S. aureus and E.coli using disc diffusion method and few of them exhibited significant antibacterial activity.
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页码：27 / 30
页数：4
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