A pool of three monoclonal antibodies, 3H12, 6D11 and 2A3, inhibited the in vitro growth of 12 Mycoplasma mycoides subspecies mycoides small colony (MmmSC) strains and seven Mycoplasma mycoides subspecies mycoides large colony (MmmLC) strains. This test did not cross-react with other 16 Mycoplasma mycoides cluster and nine non-Mycoplasma mycoides cluster strains representing 13 different species. Although MmmSC was not differentiated from MmmLC, the monoclonal antibodies distinguished both M mycoides subspecies mycoides biotypes from the other Mycoplasma species tested in contrast to results with polyclonal antisera.
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Univ Connecticut, Dept Pathobiol & Vet Sci, Connecticut Vet Med Diagnost Lab, Storrs, CT 06269 USAUniv Connecticut, Dept Pathobiol & Vet Sci, Connecticut Vet Med Diagnost Lab, Storrs, CT 06269 USA
Schumacher, Vanessa L.
Hinckley, Lynn
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Univ Connecticut, Dept Pathobiol & Vet Sci, Connecticut Vet Med Diagnost Lab, Storrs, CT 06269 USAUniv Connecticut, Dept Pathobiol & Vet Sci, Connecticut Vet Med Diagnost Lab, Storrs, CT 06269 USA
Hinckley, Lynn
Liao, Xiaofen
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机构:Univ Connecticut, Dept Pathobiol & Vet Sci, Connecticut Vet Med Diagnost Lab, Storrs, CT 06269 USA
Liao, Xiaofen
Tulman, Edan
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机构:Univ Connecticut, Dept Pathobiol & Vet Sci, Connecticut Vet Med Diagnost Lab, Storrs, CT 06269 USA
Tulman, Edan
Geary, Steven J.
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机构:Univ Connecticut, Dept Pathobiol & Vet Sci, Connecticut Vet Med Diagnost Lab, Storrs, CT 06269 USA
Geary, Steven J.
Smyth, Joan A.
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Univ Connecticut, Dept Pathobiol & Vet Sci, Connecticut Vet Med Diagnost Lab, Storrs, CT 06269 USAUniv Connecticut, Dept Pathobiol & Vet Sci, Connecticut Vet Med Diagnost Lab, Storrs, CT 06269 USA