A highly sensitive and selective turn-on fluorescent probe for sulfite and its application in biological imaging

被引:42
|
作者
Song, Jianhua [1 ]
Zhang, Di [1 ,2 ]
Liu, Yaqi [1 ]
Zhao, Yufen [1 ,3 ]
Ye, Yong [1 ,3 ]
机构
[1] Zhengzhou Univ, Phosphorus Chem Engn Res Ctr Henan Prov, Coll Chem & Mol Engn, Zhengzhou 450052, Peoples R China
[2] Henan Acad Agr Sci, Inst Agr Qual Stand & Testing Technol, Zhengzhou, Peoples R China
[3] Tsinghua Univ, Dept Chem, Key Lab Bioorgan Phosphorus Chem & Chem Biol, Minist Educ, Beijing 100084, Peoples R China
基金
美国国家科学基金会;
关键词
AQUEOUS-SOLUTION; SULFUR-DIOXIDE; CELLS; WINES; CHEMOSENSORS; MECHANISM; SYSTEM; SENSOR; WATER; ACID;
D O I
10.1039/c5nj00879d
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A turn-on fluorescein-based probe (1) has been successfully developed for the highly sensitive and selective detection of sulfite. The probe exhibits high SO32- selectivity over other common anions and biothiols (Cys, Hcy and GSH), and the detection limit was measured to be 0.55 mu M. Probe 1 exhibited high selectivity towards SO32- with a broad pH (4-9). A significant change from colorless to yellow could be directly observed by the naked eye. Furthermore, living cell imaging results demonstrated its practical application value in biological systems.
引用
收藏
页码:6284 / 6288
页数:5
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