Infertility and marker chromosomes: Application of molecular cytogenetic techniques in a case of inv dup(15)

被引：2
|
作者：
Vulcani-Freitas, TM
Gil-Da-Silva-Lopes, VL
Varella-Garcia, M
Maciel-Guerra, AT
机构：
[1] Univ Estadual Campinas, Sch Med, Dept Med Genet, BR-13083970 Campinas, SP, Brazil
[2] Univ Colorado, Ctr Canc, Denver, CO 80202 USA
[3] Hlth Sci Ctr, Denver, CO 80202 USA
来源：
JOURNAL OF APPLIED GENETICS | 2006年 / 47卷 / 01期
关键词：
cytogenetics; fluorescence in situ hybridization; inv dup (15); male infertility; spectral karyotyping;
D O I：
10.1007/BF03194605
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
We report on a phenotypically normal man with infertility, whose 47,XY,+mar karyotype was studied by spectral karyotyping (SKY) and fluorescence in situ hybridization (FISH) using a chromosome-15-specific probe (LSI SNRPN). By these techniques, the marker chromosome was identified as a small inv dup (15). Possible causes for male infertility in this case are discussed.
引用
收藏
页码：89 / 91
页数：3
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