Screening for lung cancer with low-dose computed tomography: a review of current status

被引：63
|
作者：
Marshall, Henry M. [1 ,2 ]
Bowman, Rayleen V. [1 ,2 ]
Yang, Ian A. [1 ,2 ]
Fong, Kwun M. [1 ,2 ]
Berg, Christine D. [2 ,3 ]
机构：
[1] Prince Charles Hosp, Dept Thorac Med, Brisbane, Qld 4032, Australia
[2] Univ Queensland, Sch Med, Thorac Res Ctr, Brisbane, Qld, Australia
[3] NCI, Canc Prevent Div, Bethesda, MD 20892 USA
来源：
JOURNAL OF THORACIC DISEASE | 2013年 / 5卷
基金：
英国医学研究理事会;
关键词：
Lung neoplasms/mortality; mass screening tomography; helical computed; early detection of cancer/methods; SMALL PULMONARY NODULES; MAXIMUM INTENSITY PROJECTION; TERM-FOLLOW-UP; RISK PREDICTION; RANDOMIZED FEASIBILITY; MORTALITY REDUCTION; FLEISCHNER-SOCIETY; SELECTION CRITERIA; COST-EFFECTIVENESS; SMOKING-CESSATION;
D O I：
10.3978/j.issn.2072-1439.2013.09.06
中图分类号：
R56 [呼吸系及胸部疾病];
学科分类号：
摘要：
Screening using low-dose computed tomography (CT) represents an exciting new development in the struggle to improve outcomes for people with lung cancer. Randomised controlled evidence demonstrating a 20% relative lung cancer mortality benefit has led to endorsement of screening by several expert bodies in the US and funding by healthcare providers. Despite this pivotal result, many questions remain regarding technical and logistical aspects of screening, cost-effectiveness and generalizability to other settings. This review discusses the rationale behind screening, the results of on-going trials, potential harms of screening and current knowledge gaps.
引用
收藏
页码：S524 / S539
页数：16
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