SYNTHESIS OF NEW N-SUBSTITUTED HETEROCYCLIC SULFONAMIDES

被引：0

作者：

Hangan, Adriana ^{[1
]}

Bodoki, Andreea ^{[1
]}

Oprean, Luminita ^{[1
]}

Crisan, Ovidiu ^{[2
]}

Mihalca, Ilisca ^{[3
,4
]}

机构：

[1] Univ Med & Pharm Iuliu Hatieganu, Dept Inorgan Chem, RO-400010 Cluj Napoca, Romania

[2] Univ Med & Pharm Iuliu Hatieganu, Dept Organ Chem, RO-400012 Cluj Napoca, Romania

[3] Univ Babes Bolyai, Dept Organ Chem, RO-400028 Cluj Napoca, Romania

[4] Univ Babes Bolyai, CCSOOM, RO-400028 Cluj Napoca, Romania

来源：

FARMACIA | 2012年 / 60卷 / 06期

关键词：

thiadiazoles; N-substituted sulfonamides; ligands; COPPER(II) COMPLEXES; X-RAY; DERIVATIVES; INHIBITORS;

D O I：

暂无

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

A new series of N-substituted sulfonamides derivatives of thiadiazole ring were synthesized using the Vogel method (L1-L6). The obtained compounds may coordinate a variety of metallic ions (Cu2+, Fe2+, Zn2+, Mn2+, etc.) and the resulting complexes may exhibit a wide range of biological activities (antimicrobial, anti-inflammatory, nuclease and superoxide dismutase-like activity). The structures of the newly synthesized compounds were confirmed by elemental analysis and spectroscopic (MS, IR, H-1-NMR) data.

引用

页码：932 / 938

页数：7

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