A penalized likelihood approach to estimate within-household contact networks from egocentric data

被引:4
|
作者
Potter, Gail E. [1 ,2 ]
Hens, Niel [3 ,4 ]
机构
[1] Calif Polytech State Univ San Luis Obispo, San Luis Obispo, CA 93407 USA
[2] Fred Hutchinson Canc Res Ctr, Seattle, WA 98104 USA
[3] Hasselt Univ, Diepenbeek, Belgium
[4] Univ Antwerp, Antwerp, Belgium
基金
美国国家卫生研究院;
关键词
Contact networks; Epidemic models; Household contact; Penalized network; Social networks; INFECTIOUS-DISEASE; PANDEMIC INFLUENZA; BAYESIAN-INFERENCE; TRANSMISSION; MODELS; POPULATIONS; EPIDEMICS; SPREAD;
D O I
10.1111/rssc.12011
中图分类号
O21 [概率论与数理统计]; C8 [统计学];
学科分类号
020208 ; 070103 ; 0714 ;
摘要
Acute infectious diseases are transmitted over networks of social contacts. Epidemic models are used to predict the spread of emergent pathogens and to compare intervention strategies. Many of these models assume equal probability of contact within mixing groups (homes, schools, etc.), but little work has inferred the actual contact network, which may influence epidemic estimates. We develop a penalized likelihood method to infer contact networks within households, which are a key area for disease transmission. Using egocentric surveys of contact behaviour in Belgium, we estimate within-household contact networks for six different age compositions. Our estimates show dependence in contact behaviour and vary substantively by age composition, with fewer contacts in older households. Our results are relevant for epidemic models that are used to make policy recommendations.
引用
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页码:629 / 648
页数:20
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