New cytotoxic saponins from Lysimachia davurica Ledeb.

被引：3
|
作者：
Tian, JK [1 ]
Zou, ZM
Xu, LZ
Yang, SL
机构：
[1] Zhejiang Univ, Dept Chinese Med Sci & Engn, Hangzhou 310028, Peoples R China
[2] Chinese Acad Med Sci, Inst Med Plants Dev, Beijing 100094, Peoples R China
[3] Peking Union Med Coll, Beijing 100094, Peoples R China
来源：
JOURNAL OF INTEGRATIVE PLANT BIOLOGY | 2006年 / 48卷 / 02期
关键词：
davuricoside I and E; Lysimachia davurica; triterpene saponin;
D O I：
10.1111/j.1744-7909.2006.00223.x-i1
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
To investigate the saponins from whole plants of Lysimachia davurica Ledeb., two new saponins named davuricoside I (compound 1) and E (compound 2) were isolated. Their chemical structures were elucidated as 3 beta,16 alpha, 28, 29-tetrihydroxy-olean-12-en-3-O-beta-D-glucopyranosyl-(1 --> 2)-beta-D-glucuronopyranoside (compound 1) and 3 beta,16 alpha, 29-trihydroxy-13, 28-epoxy-oleanane-3-O-beta-D-glucopyranosyl-(1 --> 2)-beta-D-glucuronopyranoside (compound 2) on the basis of their one- and two-dimensional nuclear magnetic resonance and mass spectrometry data, and chemical methods. Compound 1 showed significant cytotoxic activity against human A2780 cells.
引用
收藏
页码：232 / 235
页数：4
相关论文
共 50 条
  • [31] Cytotoxic triterpenoids from Lysimachia parvifolia
    He, Zhengchun
    Liang, Fengjie
    Lu, Jing
    Pan, Yuanjiang
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2013, 67 : 390 - 397
  • [32] A new cytotoxic triterpene saponin from Lysimachia nummularia L.
    Podolak, Irma
    Koczurkiewicz, Paulina
    Michalik, Marta
    Galanty, Agnieszka
    Zajdel, Pawel
    Janeczko, Zbigniew
    CARBOHYDRATE RESEARCH, 2013, 375 : 16 - 20
  • [33] Cytotoxic fraction from Artemisia sacrorum Ledeb. against three human cancer cell lines and separation and identification of its compounds
    Piao, Guang-Chun
    Li, Yi-Xian
    Yuan, Hai-Dan
    Jin, Guang-Zhu
    NATURAL PRODUCT RESEARCH, 2012, 26 (16) : 1483 - 1491
  • [34] Essential oil of Froriepia subpinnata (Ledeb.) Baill. from Iran
    Rustaiyan, A
    Mojab, R
    Kazemie-Piersara, M
    Bigdeli, M
    Masoudi, S
    Yari, M
    JOURNAL OF ESSENTIAL OIL RESEARCH, 2001, 13 (06) : 405 - 406
  • [35] New cytotoxic steroidal saponins from Cestrum parqui
    Mosad, Radwa R.
    Ali, Mohamed H.
    Ibrahim, Magda T.
    Shaaban, Hala M.
    Emara, Marwan
    Wahba, Amir E.
    PHYTOCHEMISTRY LETTERS, 2017, 22 : 167 - 173
  • [36] Anatomical Structure of Ectomycorrhiza in Abies sibirica Ledeb. and Picea obovata Ledeb. under Conditions of Forest Ecosystems Polluted with Emissions from Copper-Smelting Works
    D. V. Veselkin
    Russian Journal of Ecology, 2004, 35 : 71 - 78
  • [37] New cytotoxic sulfated saponins from the starfishCertonardoa semiregularis
    Weihong Wang
    Hyojin Jang
    Jongki Hong
    Chong-Ok Lee
    Song-Ja Bae
    Sook Shin
    Jee H. Jung
    Archives of Pharmacal Research, 2005, 28 : 285 - 289
  • [38] Anatomical structure of ectomycorrhiza in Abies sibiRica Ledeb. and Picea obovata Ledeb. under conditions of forest ecosystems polluted with emissions from copper-smelting works
    Veselkin, DV
    RUSSIAN JOURNAL OF ECOLOGY, 2004, 35 (02) : 71 - 78
  • [39] Cytotoxic activity of embelin from Lysimachia punctata
    Podolak, I
    Galanty, A
    Janeczko, Z
    FITOTERAPIA, 2005, 76 (3-4) : 333 - 335
  • [40] Phenotypic and fruit characterizations of Prunus divaricata Ledeb. germplasm from the north of Iran
    Khadivi, Ali
    Mirheidari, Farhad
    Moradi, Younes
    Paryan, Simin
    SCIENTIA HORTICULTURAE, 2020, 261
12345