AthaMap-assisted transcription factor target gene identification in Arabidopsis thaliana

被引:21
|
作者
Buelow, Lorenz [1 ]
Brill, Yuri [1 ]
Hehl, Reinhard [1 ]
机构
[1] Tech Univ Carolo Wilhelmina Braunschweig, Inst Genet, D-38106 Braunschweig, Germany
关键词
CIS-REGULATORY ELEMENTS; FACTOR-BINDING SITES; INFORMATION RESOURCE; WEB TOOLS; DATABASE; EXPRESSION; PATTERNS; AGRIS;
D O I
10.1093/database/baq034
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
The AthaMap database generates a map of potential transcription factor binding sites (TFBS) and small RNA target sites in the Arabidopsis thaliana genome. The database contains sites for 115 different transcription factors (TFs). TFBS were identified with positional weight matrices (PWMs) or with single binding sites. With the new web tool 'Gene Identification', it is possible to identify potential target genes for selected TFs. For these analyses, the user can define a region of interest of up to 6000 bp in all annotated genes. For TFBS determined with PWMs, the search can be restricted to high-quality TFBS. The results are displayed in tables that identify the gene, position of the TFBS and, if applicable, individual score of the TFBS. In addition, data files can be downloaded that harbour positional information of TFBS of all TFs in a region between -2000 and +2000 bp relative to the transcription or translation start site. Also, data content of AthaMap was increased and the database was updated to the TAIR8 genome release.
引用
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页数:4
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