Background: Retinaldehyde, the natural precursor of retinoic acid, should exert similar effects on photoaged skin. Objective: To establish the efficacy and safety of topical retinaldehyde on photoaged skin. Methods: Open and controlled clinical studies using image analysis of silicone skin replicas. Results: Retinaldehyde proved efficient and safe. Conclusion: Retinaldehyde is efficient and well tolerated for the improvement of the signs of photoaging.
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Univ Manchester, Ctr Dermatol Res, Fac Biol Med & Hlth, Manchester, EnglandUniv Manchester, Ctr Dermatol Res, Fac Biol Med & Hlth, Manchester, England
Kiss, O.
Halai, P.
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Univ Manchester, Ctr Dermatol Res, Fac Biol Med & Hlth, Manchester, EnglandUniv Manchester, Ctr Dermatol Res, Fac Biol Med & Hlth, Manchester, England
Halai, P.
Wang, R.
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Johns Hopkins Med, Dept Dermatol, Baltimore, MD USAUniv Manchester, Ctr Dermatol Res, Fac Biol Med & Hlth, Manchester, England
Wang, R.
Chien, A.
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Johns Hopkins Med, Dept Dermatol, Baltimore, MD USAUniv Manchester, Ctr Dermatol Res, Fac Biol Med & Hlth, Manchester, England
Chien, A.
Kang, S.
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Johns Hopkins Med, Dept Dermatol, Baltimore, MD USAUniv Manchester, Ctr Dermatol Res, Fac Biol Med & Hlth, Manchester, England
Kang, S.
O'Connor, C.
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7 Beauty Co Nottingham, Nottingham, EnglandUniv Manchester, Ctr Dermatol Res, Fac Biol Med & Hlth, Manchester, England
O'Connor, C.
Bell, M.
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7 Beauty Co Nottingham, Nottingham, EnglandUniv Manchester, Ctr Dermatol Res, Fac Biol Med & Hlth, Manchester, England
Bell, M.
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Griffiths, C.
Watson, R. E.
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Univ Manchester, Ctr Dermatol Res, Fac Biol Med & Hlth, Manchester, EnglandUniv Manchester, Ctr Dermatol Res, Fac Biol Med & Hlth, Manchester, England
Watson, R. E.
Langton, A. K.
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Univ Manchester, Ctr Dermatol Res, Fac Biol Med & Hlth, Manchester, EnglandUniv Manchester, Ctr Dermatol Res, Fac Biol Med & Hlth, Manchester, England