Frequency and Distribution of Transactive Response DNA-Binding Protein 43 (TDP-43) Pathology Across the Age Spectrum in an Elderly Cohort with and without Dementia

被引:0
|
作者
Carlos, Arenn Faye [1 ]
Tosakulwong, Nirubol [1 ]
Weigand, Stephen D. [1 ]
Boeve, Bradley F. [1 ]
Knopman, David S. [1 ]
Petersen, Ronald C. [1 ]
Nguyen, Aivi [1 ]
Reichard, Ross [1 ]
Murray, Melissa E. [2 ]
Dickson, Dennis W. [2 ]
Josephs, Keith A. [1 ]
机构
[1] Mayo Clin, Rochester, MN USA
[2] Mayo Clin, Jacksonville, FL USA
关键词
D O I
暂无
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
S120
引用
收藏
页码:S53 / S54
页数:2
相关论文
共 50 条
  • [21] Phosphorylation of TAR DNA-binding Protein of 43 kDa (TDP-43) by Truncated Casein Kinase 1 Triggers Mislocalization and Accumulation of TDP-43
    Nonaka, Takashi
    Suzuki, Genjiro
    Tanaka, Yoshinori
    Kametani, Fuyuki
    Hirai, Shinobu
    Okado, Haruo
    Miyashita, Tomoyuki
    Saitoe, Minoru
    Akiyama, Haruhiko
    Masai, Hisao
    Hasegawa, Masato
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2016, 291 (11) : 5473 - 5483
  • [22] The pathogenic mechanism of TAR DNA-binding protein 43 (TDP-43) in amyotrophic lateral sclerosis
    Wang, Xinxin
    Hu, Yushu
    Xu, Renshi
    NEURAL REGENERATION RESEARCH, 2024, 19 (04) : 800 - 806
  • [23] Point mutations in the N-terminal domain of transactive response DNA-binding protein 43 kDa (TDP-43) compromise its stability, dimerization, and functions
    Mompean, Miguel
    Romano, Valentina
    Pantoja-Uceda, David
    Stuani, Cristiana
    Baralle, Francisco E.
    Buratti, Emanuele
    Laurents, Douglas V.
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2017, 292 (28) : 11992 - 12006
  • [24] Heat Shock-induced Phosphorylation of TAR DNA-binding Protein 43 (TDP-43) by MAPK/ERK Kinase Regulates TDP-43 Function
    Li, Wen
    Reeb, Ashley N.
    Lin, Binyan
    Subramanian, Praveen
    Fey, Erin E.
    Knoverek, Catherine R.
    French, Rachel L.
    Bigio, Eileen H.
    Ayala, Yuna M.
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2017, 292 (12) : 5089 - 5100
  • [25] Transactive response DNA-binding protein 43 as a neuromarker of bipolar disorder
    Nascimento, C.
    Nunes Villela, P.
    De Oliveira, K. C.
    Barbosa, A.
    Kim, H. Kyunghee
    Moretto, A. C.
    Paraizo Leite, R. E.
    Eloah de Lucena Ferretti-Rebustini, R.
    Tenenholz Grinberg, L.
    Kimie Suemoto, C.
    Farfel, J. M.
    Pasqualucci, C. A.
    Brentani, H. P.
    Nitrini, R.
    Jacob-Filho, W.
    Lafer, B.
    BIPOLAR DISORDERS, 2018, 20 : 122 - 123
  • [26] Tar DNA-binding protein-43 (TDP-43) regulates axon growth in vitro and in vivo
    Tripathi, Vineeta Bhasker
    Baskaran, Pranetha
    Shaw, Christopher E.
    Guthrie, Sarah
    NEUROBIOLOGY OF DISEASE, 2014, 65 : 25 - 34
  • [27] Accumulation of C-terminal fragments of transactive response DNA-binding protein 43 leads to synaptic loss and cognitive deficits in human TDP-43 transgenic mice
    Medina, David X.
    Orr, Miranda E.
    Oddo, Salvatore
    NEUROBIOLOGY OF AGING, 2014, 35 (01) : 79 - 87
  • [28] TAR DNA-Binding Protein-43 (TDP-43) Aggregation in Von Economo Neurons in Early Behavioral Variant Frontotemporal Dementia
    Gaus, Stephanie E.
    Ghanta, Druthi
    Sidhu, Manu
    Miller, Bruce L.
    DeArmond, Stephen J.
    Seeley, William L.
    NEUROLOGY, 2010, 74 (09) : A96 - A96
  • [29] Distinct Patterns of Hippocampal Pathology in Alzheimer's Disease with Transactive Response DNA-binding Protein?43
    Minogue, Grace
    Kawles, Allegra
    Zouridakis, Antonia
    Keszycki, Rachel
    Macomber, Alyssa
    Lubbat, Vivienne
    Gill, Nathan
    Mao, Qinwen
    Flanagan, Margaret E.
    Zhang, Hui
    Castellani, Rudolph
    Bigio, Eileen H.
    Mesulam, M. -Marsel
    Geula, Changiz
    Gefen, Tamar
    ANNALS OF NEUROLOGY, 2023, 94 (06) : 1036 - 1047
  • [30] The role of transactive response DNA-binding protein-43 in amyotrophic lateral sclerosis and frontotemporal dementia
    Mackenzie, Ian R. A.
    Rademakers, Rosa
    CURRENT OPINION IN NEUROLOGY, 2008, 21 (06) : 693 - 700