Synthesis of multisubstituted arylsulfones via a one-pot, three-component [3+3] benzannulation reaction

被引:3
|
作者
Tang, Xiang-Zheng [1 ]
Liang, Jie [1 ]
Zhang, Xue-Jing [1 ]
Sun, Raymond Wai-Yin [2 ]
Yan, Ming [1 ]
Chan, Albert S. C. [1 ]
机构
[1] Sun Yat Sen Univ, Sch Pharmaceut Sci, Guangzhou 510006, Guangdong, Peoples R China
[2] Guangzhou Lee & Man Technol Co Ltd, Guangzhou 511458, Guangdong, Peoples R China
基金
中国国家自然科学基金;
关键词
CATALYSIS; CHEMISTRY; SULFINYL;
D O I
10.1039/c9ob00394k
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A one-pot, three-component [3 + 3] benzannulation reaction of alpha, beta-unsaturated carbonyl compounds, bromoallylic sulfones, and sodium sulfinates had been developed. A series of multisubstituted arylsulfones were prepared with moderate to good yields. This method has the advantages of good step-economy, broad substrate scope and operational simplicity.
引用
收藏
页码:4753 / 4760
页数:8
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