Novel effects of phosphodiesterase-3 (PDE3) inhibitor in preventing cardiac mitochondrial dysfunction under severe oxidative stress

被引:0
|
作者
Chattipakorn, S. [1 ]
Thommasorn, S. [2 ]
Chattipakorn, N. [2 ]
机构
[1] Chiang Mai Univ, Fac Dent, Chiang Mai 50000, Thailand
[2] Chiang Mai Univ, Fac Med, Cardiac Electrophysiol Res & Training Ctr, Chiang Mai 50000, Thailand
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:364 / 364
页数:1
相关论文
共 50 条
  • [21] Ensifentrine, A Novel, Selective Inhibitor of PDE3 and PDE4, Reduced Moderate/Severe Exacerbation Rate and Risk in Subjects With COPD Regardless of Baseline Blood Eosinophils
    Sciurba, F. C.
    Christenson, S.
    Rheault, T.
    Reyner, D.
    Bengtsson, T.
    Rickard, K.
    Barjaktarevic, I.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2024, 209
  • [22] Comparison of the protective effects of type III phosphodiesterase (PDE3) inhibitor (cilostazol) and acetylsalicylic acid on intestinal microcirculation after ischemia reperfusion injury in mice
    Iba, Toshiaki
    Kidokoro, Akio
    Fukunaga, Masaki
    Takuhiro, Kitoji
    Ouchi, Masakazu
    Ito, Yoshitomo
    SHOCK, 2006, 26 (05): : 522 - 526
  • [23] MC2, a new phosphodiesterase-3 inhibitor with antilipolytic and hypolipidemic effects in normal and diabetic rats
    Alinejad, Bagher
    Shafiee-Nick, Reza
    Ghorbani, Ahmad
    Sadeghian, Hamid
    INTERNATIONAL JOURNAL OF DIABETES IN DEVELOPING COUNTRIES, 2015, 35 (04) : 408 - 417
  • [24] Efficacy of melatonin and its metabolites in preventing oxidative stress and mitochondrial dysfunction under conditions of sepsis
    Lowes, D. A.
    Webster, N. R.
    Galley, H. F.
    BRITISH JOURNAL OF ANAESTHESIA, 2013, 111 (02) : 309P - 309P
  • [25] Elevation of cyclic AMP and cyclic GMP levels by phosphodiesterase3 (PDE3) inhibitor attenuates ischemia and reperfusion injury of canine livers.
    Ishikawa, H
    Taniguchi, M
    Suzuki, T
    Shimamura, T
    Jin, MB
    Horiuchi, H
    Iida, J
    Magata, S
    Ogata, K
    Yokota, R
    Fukai, M
    Kishida, A
    Furukawa, H
    Todo, S
    TRANSPLANTATION, 1999, 67 (07) : S79 - S79
  • [26] Synthesis and evaluation of novel 2-pyridone derivatives as inhibitors of phosphodiesterase3 (PDE3): A target for heart failure and platelet aggregation
    Ravinder, Mettu
    Mahendar, Budde
    Mattapally, Saidulu
    Hamsini, Kommi Venkata
    Reddy, Thatikonda Narendar
    Rohit, Chilappa
    Srinivas, Kolupula
    Banerjee, Sanjay Kumar
    Rao, Vaidya Jayathirtha
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2012, 22 (18) : 6010 - 6015
  • [27] Oxidative stress-induced glucocorticoid resistance is prevented by dual PDE3/PDE4 inhibition in human alveolar macrophages
    Milara, J.
    Navarro, A.
    Almudever, P.
    Lluch, J.
    Morcillo, E. J.
    Cortijo, J.
    CLINICAL AND EXPERIMENTAL ALLERGY, 2011, 41 (04): : 535 - 546
  • [28] Effect of the Phosphodiesterase 5 Inhibitor Sildenafil on Ischemia-Reperfusion-Induced Muscle Mitochondrial Dysfunction and Oxidative Stress
    Tetsi, Liliane
    Charles, Anne-Laure
    Georg, Isabelle
    Goupilleau, Fabienne
    Lejay, Anne
    Talha, Samy
    Maumy-Bertrand, Myriam
    Lugnier, Claire
    Geny, Bernard
    ANTIOXIDANTS, 2019, 8 (04)
  • [29] Phosphodiesterase PDE3 blunts the positive inotropic and cyclic AMP enhancing effects of CGP12177 but not of noradrenaline in rat ventricle
    Vargas, ML
    Hernandez, J
    Kaumann, AJ
    BRITISH JOURNAL OF PHARMACOLOGY, 2006, 147 (02) : 158 - 163
  • [30] A Novel Nutraceuticals Mixture Improves Liver Steatosis by Preventing Oxidative Stress and Mitochondrial Dysfunction in a NAFLD Model
    Sangineto, Moris
    Bukke, Vidyasagar Naik
    Bellanti, Francesco
    Tamborra, Rosanna
    Moola, Archana
    Duda, Loren
    Villani, Rosanna
    Romano, Antonino Davide
    Serviddio, Gaetano
    NUTRIENTS, 2021, 13 (02) : 1 - 13