An overview of psoriatic arthritis - epidemiology, clinical features, pathophysiology and novel treatment targets

被引:32
|
作者
Kerschbaumer, Andreas [1 ,2 ]
Fenzl, Karl H. [2 ]
Erlacher, Ludwig [2 ,3 ]
Aletaha, Daniel [1 ]
机构
[1] Med Univ Vienna, Div Rheumatol, Dept Internal Med 3, Wahringer Gurtel 18-20, A-1090 Vienna, Austria
[2] Karl Landsteiner Inst Autoimmune Dis & Rheumatol, Kundratstr 3, A-1100 Vienna, Austria
[3] 2nd Med Dept Rheumatol Osteol & Geriatr, Kundratstr 3, A-1100 Vienna, Austria
关键词
Psoriatic arthritis; Clinical aspects; Epidemiology; Treatment; Pathophysiology; RHEUMATOID-ARTHRITIS; IMMUNE REGULATION; BIOLOGIC THERAPY; CONTROLLED-TRIAL; HIGH PREVALENCE; DISEASE; PATHOGENESIS; RISK; INFLAMMATION; ENTHESITIS;
D O I
10.1007/s00508-016-1111-9
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Psoriatic arthritis is a chronic inflammatory joint disease occurring in a subgroup of patients suffering from psoriasis. This article gives an overview of the complexity of psoriatic arthritis, looking at several aspects of this heterogeneous disease, such as epidemiology, important clinical features and comorbidities as well as current concepts of the pathophysiology and subsequent insights in novel treatment targets.
引用
收藏
页码:791 / 795
页数:5
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